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基于临床样本的儿科有先兆偏头痛频率。

Frequency of pediatric migraine with aura in a clinic-based sample.

机构信息

Department of Pediatrics, Bnai Zion Medical Center, Haifa, Israel.

Pediatric Neurology Unit, Bnai Zion Medical Center, Haifa, Israel.

出版信息

Headache. 2016 Jan;56(1):113-7. doi: 10.1111/head.12741. Epub 2015 Dec 21.

Abstract

OBJECTIVE

To assess the prevalence and risk factors for pediatric migraine with aura (MWA) among patients presenting to pediatric neurology clinics.

BACKGROUND

Headache is a common complaint among children, and the prevalence of migraine is about 8%. Up to one third of adults with migraine report experiencing aura; however, the exact percentage in children is unknown.

METHODS

Medical records of children presenting with headache to three pediatric neurology clinics in Haifa in the last 5 years were retrospectively reviewed. Inclusion criteria were a diagnosis of migraine headache at 5-18 years of age.

RESULTS

Of 260 children (140 female) who had migraine, 26.2% experienced aura. MWA was more common among females compared to males (32.6% vs 18.9%, P < .01) and among older children (OR: 2.50, 95% CI: 1.20-5.20; P < .01). Among those who experienced aura, visual aura was more common in females than males (66.7% vs 33.3%, P < .04). Family history of migraine was strongly related to MWA (P < .02): the odds of MWA were 2.46 times greater in children who had a family history of migraine. (OR: 2.46, 95% CI: 1.08-5.62; P < .03).

CONCLUSIONS

MWA is as common in children as in adults. Aura is more common in older children. Children who have MWA are more likely to have a family history of migraine.

摘要

目的

评估儿科神经内科就诊患儿中出现先兆偏头痛(MWA)的患病率和危险因素。

背景

头痛是儿童常见的主诉,偏头痛的患病率约为 8%。多达三分之一的成年偏头痛患者报告有先兆;然而,儿童中确切的百分比尚不清楚。

方法

回顾性分析了过去 5 年在海法的三家儿科神经内科就诊的出现头痛的 260 名儿童(140 名女性)的病历。纳入标准为 5-18 岁诊断为偏头痛头痛。

结果

在 260 名患有偏头痛的儿童(140 名女性)中,26.2%出现先兆。与男性相比,女性中 MWA 更为常见(32.6%比 18.9%,P<.01),且年长儿童更为常见(OR:2.50,95%CI:1.20-5.20;P<.01)。在出现先兆的患者中,女性出现视觉先兆的比例高于男性(66.7%比 33.3%,P<.04)。偏头痛家族史与 MWA 密切相关(P<.02):有偏头痛家族史的儿童发生 MWA 的几率是无家族史儿童的 2.46 倍。(OR:2.46,95%CI:1.08-5.62;P<.03)。

结论

MWA 在儿童中的发病率与成年人相同。先兆更常见于年长儿童。患有 MWA 的儿童更有可能有偏头痛家族史。

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