Shapiro Hannah F J, Lebel Alyssa
Department of Child Neurology, Boston Children's Hospital, Boston, MA 02115, USA.
Division of Pain Medicine, Department of Anesthesiology, Boston Children's Hospital, Boston, MA 02115, USA.
Children (Basel). 2021 Mar 17;8(3):228. doi: 10.3390/children8030228.
Migraine headache is a common cause of pain and disability in children and adolescents and is a major contributor to frequently missed school days and limitations in activities. Of children and adolescents with migraine headache, approximately one-third have migraine with aura (MA). MA is often considered to be similar to migraine without aura (MO), and thus, many studies do not stratify patients based on the presence of aura. Because of this, treatment recommendations are often analogous between MA and MO, with a few notable exceptions. The purpose of this review is to highlight the current evidence demonstrating the unique pathophysiology, clinical characteristics, differential diagnosis, co-morbidities, and treatment recommendations and responses for pediatric MA.
偏头痛是儿童和青少年疼痛及残疾的常见原因，也是导致频繁缺课和活动受限的主要因素。在患有偏头痛的儿童和青少年中，约三分之一患有先兆偏头痛（MA）。MA通常被认为与无先兆偏头痛（MO）相似，因此，许多研究并未根据是否存在先兆对患者进行分层。正因如此，MA和MO的治疗建议通常类似，但也有一些明显的例外。本综述的目的是强调当前的证据，这些证据表明了儿童MA独特的病理生理学、临床特征、鉴别诊断、合并症以及治疗建议和反应。
