Silverman Edward J, Ashley Blair, Sheth Neil P
Department of Orthopaedics, The University of Pennsylvania Health System, 800 Spruce Street, Philadelphia, PA, 19107, USA.
Curr Rev Musculoskelet Med. 2016 Mar;9(1):93-6. doi: 10.1007/s12178-016-9323-1.
The use of metal-on-metal (MoM) bearings in total hip arthroplasty (THA) was popularized due to its enhanced wear profile and the ability to use large femoral heads to reduce post-operative instability. However, enthusiasm for the bearing declined following serious complications encountered at the primary articulation. This review discusses the development of MoM and the subsequent unexpected downstream challenges, most notably elevated serum metal ion levels, aseptic lymphocyte-dominated vasculitis-associated lesions (ALVAL), pseudotumor formation, and subsequent soft tissue and bone destruction. Both patient centered risk factors as well as component design led to high early failure rates resulting in product recalls and an overall decline in the use of MoM. In 2016, there is not a role for large-head MoM bearing in THA. Alternatively, the bearing has shown promise in hip resurfacing procedures for carefully selected patients.
金属对金属(MoM)轴承在全髋关节置换术(THA)中的应用因具有改善的磨损情况以及使用大尺寸股骨头以减少术后不稳定的能力而得到推广。然而,在初次关节置换时出现严重并发症后,人们对这种轴承的热情有所下降。本综述讨论了MoM的发展以及随后出现的意外下游挑战,最显著的是血清金属离子水平升高、无菌性淋巴细胞为主的血管炎相关病变(ALVAL)、假瘤形成以及随后的软组织和骨破坏。以患者为中心的风险因素以及部件设计都导致了较高的早期失败率,从而引发产品召回,MoM的使用总体上也有所下降。2016年,大头MoM轴承在THA中已无应用价值。另外,这种轴承在为精心挑选的患者进行的髋关节表面置换手术中显示出了前景。