García Pérez A, Caritg Bosch J, Juncosa Morros T, Krauel Vidal J
Servicio de Neonatología, Hospital Infantil de San Juan de Dios, Barcelona.
An Esp Pediatr. 1989 Jun;30(6):480-2.
Described is an outbreak of nosocomial RSV infection, following the admission of a 20-day-old and 11-day-old newborn with lower respiratory infections, diagnosed as being caused by RSV through detection of viral antigens by direct FAT (fluorescent antibody test) of nasopharyngeal samples. Later on, 5 of the other 20 newborn in patients in the same care unit also showed positive results in direct FAT, for RSV. The clinical manifestations of these patients were mild even in those cases with underlying PHT and cardiac disease and consisted of: cough (5/5), nasal discharge (3/5), poor feeding (1/5), sneezing (1/5), distress (1/5) and irritability (1/5). The rapid diagnosis of RSV though the direct FAT enables us to establish hygienic restrictions and patients isolation to keep the virus from spreading.
描述了一起医院内呼吸道合胞病毒(RSV)感染的暴发事件,此次暴发是在一名20日龄和一名11日龄的新生儿因下呼吸道感染入院后发生的,通过对鼻咽样本进行直接荧光抗体试验(FAT)检测病毒抗原,诊断为由RSV引起。后来,同一护理单元的其他20名新生儿患者中有5名在RSV直接FAT检测中也呈阳性结果。这些患者的临床表现即使在合并潜在肺动脉高压(PHT)和心脏病的病例中也很轻微,包括:咳嗽(5/5)、流涕(3/5)、喂养困难(1/5)、打喷嚏(1/5)、呼吸窘迫(1/5)和易激惹(1/5)。通过直接FAT快速诊断RSV使我们能够制定卫生限制措施并隔离患者,以防止病毒传播。