Dendy Meaghan, Johnson Katelyn, Boffa Daniel J
Department of Thoracic Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
J Thorac Dis. 2015 Dec;7(12):E648-51. doi: 10.3978/j.issn.2072-1439.2015.11.64.
Esophageal leiomyomas are rare benign tumors that can be treated successfully with limited surgical resection. It is occasionally important to distinguish leiomyomas from more aggressive submucosal esophageal tumors, most notably gastrointestinal stromal tumors (GISTs). GISTs have a worse prognosis, particularly when they are large (>10 cm). Increased uptake of (18)F-fluorodeoxyglucose on positron emission tomography (PET) scans is common in GISTs, potentially allowing PET scanning to differentiate between GIST and benign esophageal tumors. Three patients presented with large (>10 cm) esophageal masses of ranging PET avidity [maximum standardized uptake value (SUVmax) of 1.3-10.1]. All were treated surgically and histologically confirmed to be esophageal leiomyomas. Unfortunately, the wide range of PET uptake precludes PET scanning from differentiating large leiomyomas from more aggressive lesions.
食管平滑肌瘤是罕见的良性肿瘤,可通过有限的手术切除成功治疗。偶尔,区分平滑肌瘤与更具侵袭性的食管黏膜下肿瘤,尤其是胃肠道间质瘤(GIST)很重要。GIST的预后较差,尤其是当肿瘤较大(>10 cm)时。在正电子发射断层扫描(PET)中,GIST常见(18)F-氟脱氧葡萄糖摄取增加,这可能使PET扫描能够区分GIST和良性食管肿瘤。三名患者出现了PET摄取程度不同的大(>10 cm)食管肿块[最大标准化摄取值(SUVmax)为1.3 - 10.1]。所有患者均接受了手术治疗,组织学证实为食管平滑肌瘤。不幸的是,PET摄取范围广泛,使得PET扫描无法区分大的平滑肌瘤与更具侵袭性的病变。