Department of Gastroenterology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa, 241-8515, Japan.
Department of Gastroenterology, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.
Clin J Gastroenterol. 2022 Feb;15(1):53-58. doi: 10.1007/s12328-021-01535-y. Epub 2021 Oct 22.
For an esophageal submucosal mass suspicious of granular cell tumor (GCT) based on gross appearance and endoscopic ultrasound findings, a sufficient number of biopsy specimens is required for a definite diagnosis using immunohistochemical examination. When the specimen obtained by forceps biopsy is insufficient, endoscopic ultrasound-fine needle aspiration (EUS-FNA) is believed to be an useful alternative. However, it may be difficult to obtain an adequate amount of tumor material using EUS-FNA. Mucosal incision-assisted biopsy (MIAB) is a simple method that can collect larger amounts of specimens. This procedure is helpful for physicians who encounter the problem of obtaining an adequate amount of biopsy material from esophageal tumors suspicious for GCT. We present a case of esophageal GCT that was successfully diagnosed through MIAB.
对于外观和内镜超声检查怀疑为颗粒细胞瘤（GCT）的食管黏膜下肿块，如果要通过免疫组织化学检查明确诊断，则需要足够数量的活检标本。当钳夹活检获得的标本不足时，内镜超声引导下细针抽吸（EUS-FNA）被认为是一种有用的替代方法。然而，通过 EUS-FNA 可能难以获得足够量的肿瘤材料。黏膜切开辅助活检（MIAB）是一种可以收集更多标本的简单方法。对于遇到从疑似 GCT 的食管肿瘤中获得足够量活检材料的问题的医生来说，该方法很有帮助。我们报告了一例成功通过 MIAB 诊断的食管 GCT 病例。
