Tolofari Sotonye Karl, Chow Wai-Man, Hussain Basharat
North Manchester General Hospital, Delaunays Road, Manchester, Greater Manchester M8 5RB, United Kingdom.
Urol Case Rep. 2015 Jan 16;3(2):24-6. doi: 10.1016/j.eucr.2014.11.003. eCollection 2015 Mar.
Castleman's disease is a rare benign lymphoproliferative disorder, characterized by benign growths of the lymph node tissue. It is associated with a number of malignancies, including Kaposi sarcoma, non-Hodgkin's and Hodgkins lymphoma, and POEMS syndrome. This report describes the case of a 38 year old gentleman, presenting with painless hematuria. Initial investigations, including flexible cystoscopy were unremarkable. However, subsequent imaging including CT Urogram and MR pelvis revealed multiple prevesical lesions. Histology obtained from excision biopsy revealed histological features consistent with Castleman's disease. In this report we discuss the nature, presentation and treatment modalities of this rare condition.