结合蛋白的分离：负责精子与海胆卵黏附的蛋白质。

Vacquier V D, Moy G W

Proc Natl Acad Sci U S A. 1977 Jun;74(6):2456-60. doi: 10.1073/pnas.74.6.2456.

The insoluble granular material of the acrosome vesicle of sea urchin sperm has been isolated and shown to be a single 30,500 dalton protein for which the name "bindin" is proposed. The data presented are consistent with the hypothesis that bindin is the adhesive responsible for the attachment of sperm to the vitelline layer of the egg. Experimental results suggest that bindin may act by binding to carbohydrate receptors of vitelline layer glycoproteins. The speculation is made that sperm bindins may be the general mechanism by which animal sperm attach to eggs.

海胆精子顶体小泡中的不溶性颗粒物质已被分离出来，结果表明它是一种单一的30500道尔顿的蛋白质，为此提议将其命名为“结合素”。所呈现的数据与这样一种假说相符，即结合素是负责精子附着于卵黄膜的黏附剂。实验结果表明，结合素可能通过与卵黄膜糖蛋白的碳水化合物受体结合而起作用。有人推测，精子结合素可能是动物精子附着于卵子的普遍机制。