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严重毁损肢体的一期截肢与保肢治疗:当前评分系统的系统评价

Primary amputation vs limb salvage in mangled extremity: a systematic review of the current scoring system.

作者信息

Schirò Giuseppe Rosario, Sessa Sergio, Piccioli Andrea, Maccauro Giulio

机构信息

Niguarda Cà Granda Hospital, Piazza Ospedale Maggiore 3, 20162, Milan, Italy.

Galeazzi Orthopaedic Hospital, Milan, Italy.

出版信息

BMC Musculoskelet Disord. 2015 Dec 2;16:372. doi: 10.1186/s12891-015-0832-7.

Abstract

BACKGROUND

In the last decades a lot of new reconstructive techniques were developed for the treatment of mangled lower extremity. However failed attempt to limb salvage is related to high risk of mortality for the patient. Several scores were developed to establish guidelines for the decision to amputate or not, however in literature there is no consensus about the reliability of this scores.

METHODS

The authors focused their attention on the most used score system to provide guidance of the management of a mangled lower limb. The search term used included mangled lower extremity, MESS, PSI, LSI and NISSSA. The inclusion criteria were: studies dealing with mangled lower extremity; articles reporting MESS, PSI, LSI or NISSSA scores; articles published in English in PubMed, Cochrane, Scopus and web of science in the last 30 years, minimum number of cases in study of 15, minimum follow up of 1 year.

RESULTS

According with the criteria described above, we found 134 articles in PubMed, 165 articles in Scopus, 111 articles in the Cochrane Library and 108 articles in Web of Science. The most used score in literature is the MESS. Few results are shown using the other severity scores. There are a lot of controversies in literature about the use of this scale. MESS seems to be more accurate than the LSI in prediction of limb salvage. LSI score shows better results when applied to type III tibial fractures. High sentivity of the PSI score is described when applied to predict successful limb salvage. Low sensitivity and specificity are described for the NISSSA score. The literature is very poor of articles related to mangled lower extremity in children. Higher sensitivity and specificity are described for these scores in children when compared to adult population.

CONCLUSION

The mangled lower extremity treatment is a challenge for the surgeon. Many scores were developed to help the surgeon, however they cannot be used as the sole criterion by which amputation decision are made and, in case of succesful limb salvage, they are not predictive of the functional recovery. Moreover, undue enthusiasm for new surgical techniques can lead to increased morbidity and mortality in case of secondary amputation.

摘要

背景

在过去几十年中,为治疗严重毁损的下肢开发了许多新的重建技术。然而,保肢手术的失败尝试与患者的高死亡风险相关。已经开发了几种评分系统来为截肢与否的决策制定指南,然而在文献中对于这些评分系统的可靠性尚无共识。

方法

作者将注意力集中在最常用的评分系统上,以指导严重毁损下肢的治疗。使用的检索词包括严重毁损的下肢、MESS、PSI、LSI和NISSSA。纳入标准为:涉及严重毁损下肢的研究;报告MESS、PSI、LSI或NISSSA评分的文章;过去30年在PubMed、Cochrane、Scopus和科学网以英文发表的文章,研究中病例数最少为15例,随访时间最少为1年。

结果

根据上述标准,我们在PubMed中找到134篇文章,在Scopus中找到165篇文章,在Cochrane图书馆中找到111篇文章,在科学网中找到108篇文章。文献中最常用的评分是MESS。使用其他严重程度评分的结果较少。关于该量表的使用,文献中有很多争议。在预测保肢方面,MESS似乎比LSI更准确。LSI评分应用于III型胫骨骨折时显示出更好的结果。当应用PSI评分预测保肢成功时,其敏感性较高。NISSSA评分的敏感性和特异性较低。关于儿童严重毁损下肢的文章在文献中非常少。与成人相比,这些评分在儿童中的敏感性和特异性更高。

结论

严重毁损下肢的治疗对外科医生来说是一项挑战。已经开发了许多评分来帮助外科医生,然而它们不能作为做出截肢决定的唯一标准,并且在保肢成功的情况下,它们不能预测功能恢复。此外,对新手术技术的过度热情可能会导致二次截肢时发病率和死亡率增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018b/4722671/f68478143a10/12891_2015_832_Fig1_HTML.jpg

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