Pang Renée, Merritt Neil H, Shkrum Michael J, Tijssen Janice A
Department of Pediatrics, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada; and University of Western Ontario, London, Ontario, Canada.
University of Western Ontario, London, Ontario, Canada University Hospital, London Health Sciences Centre, London, Ontario, Canada; and.
Pediatrics. 2016 Feb;137(2):e20143544. doi: 10.1542/peds.2014-3544. Epub 2016 Jan 21.
We report a case of a child with a right ventricular inflammatory myofibroblastic tumor (IMT) who presented with fever, viral symptoms, and abdominal discomfort. Including this case, 49 intracardiac tumors have been previously reported in all age groups. The majority of intracardiac IMTs occur in pediatric patients, with approximately half presenting in children aged <12 months. Intracardiac IMTs are generally described as benign tumors; however, depending on their location, the initial presentation may involve heart failure or sudden death.(1) In addition to cardiac signs and symptoms, the clinical presentation of IMTs may also include constitutional signs such as fever, anemia, and elevated inflammatory markers. This case report reviews the diagnosis and management of IMTs, as well as the histopathologic features of this rare tumor type. Clinicians should be aware of their clinical presentation because early diagnosis and treatment can significantly reduce morbidity and mortality.
我们报告了一例患有右心室炎性肌纤维母细胞瘤(IMT)的儿童,该患儿表现为发热、病毒感染症状和腹部不适。包括该病例在内,此前已报道了所有年龄组的49例心脏肿瘤。大多数心脏IMT发生在儿科患者中,约一半出现在12个月以下的儿童中。心脏IMT通常被描述为良性肿瘤;然而,根据其位置,最初的表现可能涉及心力衰竭或猝死。(1)除了心脏体征和症状外,IMT的临床表现还可能包括发热、贫血和炎症标志物升高等全身症状。本病例报告回顾了IMT的诊断和治疗,以及这种罕见肿瘤类型的组织病理学特征。临床医生应了解其临床表现,因为早期诊断和治疗可显著降低发病率和死亡率。