Doroudinia Abtin, Kaghazchi Fatemeh, Mehrian Payam, Dorudinia Atosa
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Radiology, Telemedicine Research Center (TRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMJ Case Rep. 2018 Jul 13;2018:bcr-2018-224373. doi: 10.1136/bcr-2018-224373.
Inflammatory myofibroblastic tumour (IMT) is a rare neoplasm, occurring most often in children and young adults. IMTs have intermediate biological behaviour with the chance of local invasion, recurrence and even distant metastasis. Wide range of clinical presentations makes the precise diagnosis of IMT more challenging. The best method for definitive diagnosis is tissue biopsy and newer imaging modalities including fleurodeoxyglucose (FDG) positron emission tomography (PET)/CT are useful tools in detection of disease recurrence or distant metastasis. Complete surgical resection is the best-known treatment for this tumour. Here we are presenting an IMT case in a 12-year-old girl in which her recurrent pulmonary IMT was diagnosed based on FDG PET/CT findings and referred for further salvage treatment. Overall imaging modalities are not specific, but PET/CT scan can be useful tool for evaluation of IMT regarding initial staging and restaging to assess treatment response and recurrence.
炎性肌纤维母细胞瘤（IMT）是一种罕见的肿瘤，最常发生于儿童和年轻人。IMT具有中间型生物学行为，有局部侵袭、复发甚至远处转移的可能。广泛的临床表现使得IMT的准确诊断更具挑战性。确诊的最佳方法是组织活检，包括氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）/CT在内的新型成像方式是检测疾病复发或远处转移的有用工具。完整的手术切除是该肿瘤最知名的治疗方法。在此，我们报告一例12岁女孩的IMT病例，其复发性肺IMT基于FDG PET/CT检查结果得以确诊，并被转诊接受进一步的挽救治疗。总体而言，成像方式并不具有特异性，但PET/CT扫描对于评估IMT的初始分期和再分期以评估治疗反应及复发情况可能是一种有用的工具。
