晚年的土地利用混合与五年死亡率：认知功能与衰老研究的结果
Land use mix and five-year mortality in later life: Results from the Cognitive Function and Ageing Study.
作者信息
Wu Yu-Tzu, Prina A Matthew, Jones Andy, Barnes Linda E, Matthews Fiona E, Brayne Carol
机构信息
Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, University of Cambridge, School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge CB2 0SR, United Kingdom.
Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, University of Cambridge, School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge CB2 0SR, United Kingdom; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Centre for Global Mental Health, Health Service and Population Research Department, De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom.
出版信息
Health Place. 2016 Mar;38:54-60. doi: 10.1016/j.healthplace.2015.12.002. Epub 2016 Feb 1.
This study explores the potential modifying effect of age and mediation effect of co-morbidity on the association between land use mix, a measure of neighbourhood walkability, and five-year mortality among the 2424 individuals participating in the year-10 follow-up of the Cognitive Function and Ageing Study in England. Postcodes of participants were mapped onto Lower-layer Super Output Areas, a small area level geographical unit in the UK, and linked to Generalised Land Use data. Cox regression models were fitted to investigate the association. For the younger older age group (75-79 years), the effect of high land use mix on an elevated risk of mortality was mediated by co-morbidity. For older old age groups (80-84, 85+ years), a higher land use mix was directly associated with a 10% lower risk of five-year mortality. The findings suggest differential impacts of land use mix on the health of the younger and older old.
本研究探讨了年龄的潜在调节作用以及共病在土地利用混合（一种邻里步行适宜性的衡量指标）与参与英格兰认知功能与衰老研究10年随访的2424名个体的五年死亡率之间关联中的中介作用。参与者的邮政编码被映射到英国的一个小区域地理单元——下层超级输出区，并与广义土地利用数据相关联。采用Cox回归模型来研究这种关联。对于较年轻的老年组（75 - 79岁），土地利用混合程度高对死亡率升高风险的影响通过共病起中介作用。对于高龄老年组（80 - 84岁、85岁及以上），较高的土地利用混合程度与五年死亡率风险降低10%直接相关。研究结果表明，土地利用混合对年轻老年人和高龄老年人的健康有不同影响。
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