Ivanov S D, Komar V E, Teslenko V M, Znamenskiĭ V V, Barkaia V S, Torua R A
Biull Eksp Biol Med. 1989 Aug;108(8):158-9.
Changes of Macaca nemestrina and Rhesus blood DNA have been studied up to 5 days after the total uniform gamma-irradiation in doses 6.2 and 6.5 Gy. The content of nucleotide ATrich DNA has been evaluated in the fractions of leucocytes with the various surface adherence properties. The dynamics of the content nucleotide AT-DNA and blood leucocytes were similar at the both monkey species. The evaluation of structural state DNA in the blood nucleotide with the fluorescent dyes (ethidium bromide and 4; 6-diamidine-2-phenylindole) demonstrated that the important changes in the polynucleotide structure occurred from 6 to 24 h after irradiation and maintained up to 5 days. Adhesive capacity changes were reversible but they preceded the DNA structural changes. At 24 h postirradiation non-adhesive cells with relative higher AT-DNA content were found.
对食蟹猴和恒河猴在接受6.2和6.5 Gy的全身均匀γ射线照射后长达5天的血液DNA变化进行了研究。已在具有不同表面黏附特性的白细胞组分中评估了富含核苷酸AT的DNA含量。在这两种猴类中，核苷酸AT-DNA含量和血液白细胞的动态变化相似。用荧光染料（溴化乙锭和4,6-二脒基-2-苯基吲哚）对血液核苷酸中DNA的结构状态进行评估表明，照射后6至24小时多核苷酸结构发生了重要变化，并持续至5天。黏附能力变化是可逆的，但它们先于DNA结构变化出现。照射后24小时发现了具有相对较高AT-DNA含量的非黏附细胞。
