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[血液核苷酸DNA的结构变化与受辐照大鼠后期后遗症的发展]

[Structural changes in the DNA of the blood nucleotides and the development of late sequelae in irradiated rats].

作者信息

Ivanov S D, Remizova I V, Kovan'ko E G, Gubareva A V, Komar V E

出版信息

Biull Eksp Biol Med. 1990 Mar;109(3):296-9.

PMID:2194584
Abstract

Fluorescent analysis of structural changes of nucleotide in the blood associated with AT fragments has been studied in rats, gamma-irradiated with doses of 2 and 4 Gy. It was demonstrated that the haematological, gerontological and cancerogenic late consequences were preceded by the structural genomic disturbances determined by 30 day after irradiation.

摘要

对受2戈瑞和4戈瑞剂量γ射线照射的大鼠血液中与AT片段相关的核苷酸结构变化进行了荧光分析。结果表明,血液学、老年学和致癌的晚期后果之前,在照射后30天就已出现由结构基因组紊乱所决定的情况。

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