Fukushima Munehisa, Oya Ryohei, Akazawa Hitoshi, Tsuruta Yukinori, Inohara Hidenori
a Department of Otolaryngology/Head and Neck Surgery , Kansai Rosai Hospital , Hyogo , Japan ;
b Department of Otolaryngology/Head and Neck Surgery , Osaka University, Graduate School of Medicine , Osaka , Japan.
Acta Otolaryngol. 2016;136(5):451-5. doi: 10.3109/00016489.2015.1129554. Epub 2016 Jan 22.
The data suggests that gadolinium-enhanced inner ear MR imaging is useful for diagnosis of delayed endolymphatic hydrops (DEH) because it is independent of inner ear function, and the size of the affected endolymphatic space is clearly enlarged.
This study was performed to semi-quantitatively evaluate the endolymphatic space in patients with all types of DEH using gadolinium-enhanced inner ear magnetic resonance (MR) imaging.
Seven patients (age range = 21-77 years; five female, two male) with ipsilateral DEH (n = 5), contralateral DEH (n = 1), and bilateral DEH (n = 1). All patients underwent 3T MR imaging 4 h after intravenous injection of gadolinium. Software was used to determine the size of the endolymphatic space. Pure tone audiometry and caloric testing using an electronystagmogram were carried out.
One side of the endolymphatic space was dominantly extended in patients with ipsilateral DEH, and both sides of the space were extended in patients with contralateral and bilateral DEH. In patients with ipsilateral DEH, the volume ratio of endolymph to vestibule was 2.5-4.3-times that in the unaffected ear. The volume ratio of endolymph to vestibule was nearly equal in patients with contralateral and bilateral DEH.
数据表明，钆增强内耳磁共振成像对于诊断迟发性内淋巴积水（DEH）很有用，因为它不依赖内耳功能，且受累内淋巴间隙明显扩大。
本研究旨在使用钆增强内耳磁共振成像对所有类型DEH患者的内淋巴间隙进行半定量评估。
7例患者（年龄范围21 - 77岁；5例女性，2例男性），其中同侧DEH患者5例、对侧DEH患者1例、双侧DEH患者1例。所有患者在静脉注射钆后4小时接受3T磁共振成像检查。使用软件确定内淋巴间隙大小。进行纯音听力测定和使用眼震电图的冷热试验。
同侧DEH患者内淋巴间隙一侧显著扩大，对侧和双侧DEH患者内淋巴间隙两侧均扩大。同侧DEH患者内淋巴与前庭的体积比是未受累耳的2.5 - 4.3倍。对侧和双侧DEH患者内淋巴与前庭的体积比几乎相等。
