Bunyavaree Monthathip, Kasemsarn Pranee, Boonchai Waranya
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Contact Dermatitis. 2016 Apr;74(4):217-21. doi: 10.1111/cod.12520. Epub 2016 Jan 22.
Preservatives are added to cosmetics and other consumer products to prevent microbial growth and product degradation. Many cosmetic preservatives are skin sensitizers and frequent causes of contact dermatitis. The use of preservatives may vary by country and/or region, according to legislation, and may be reflected in differences in the prevalence rates of preservative allergy worldwide.
To examine the type and frequency of preservative use in cosmetics sold in Thai markets in metropolitan Bangkok, Thailand.
Preservatives contained in 1000 different cosmetics sold in Thai markets were documented and analysed, based on the labelling of ingredients.
Most of the cosmetic and skincare products sold in Thai markets were international brands, with only a small proportion of cosmetic products being produced in Thailand. International brand cosmetics were more likely to contain non-formaldehyde-releasing preservatives than domestically produced brands. Isothiazolinone-based preservatives, which are responsible for the current increase in the prevalence of contact allergy, were found at a significant frequency in domestically produced, leave-on cosmetic products.
Preservatives in cosmetics were significantly different according to source of production and type of cosmetics.
防腐剂被添加到化妆品和其他消费品中以防止微生物生长和产品变质。许多化妆品防腐剂是皮肤致敏剂,也是接触性皮炎的常见病因。根据法规,防腐剂的使用在不同国家和/或地区可能有所不同,这可能反映在全球防腐剂过敏患病率的差异上。
研究泰国曼谷大都市地区泰国市场销售的化妆品中防腐剂的使用类型和频率。
根据成分标签,记录并分析泰国市场销售的1000种不同化妆品中所含的防腐剂。
泰国市场销售的大多数化妆品和护肤品都是国际品牌,只有一小部分化妆品是泰国生产的。国际品牌化妆品比国内生产的品牌更有可能含有非释放甲醛的防腐剂。导致目前接触性过敏患病率上升的异噻唑啉酮类防腐剂在国内生产的留用化妆品中出现的频率很高。
化妆品中的防腐剂因生产来源和化妆品类型而有显著差异。