Blanchy S, Benthein F
Médecin inspecteur en chef de la santé, ex-responsable de la Section de lutte anti-paludique, Bordeaux.
Bull Soc Pathol Exot Filiales. 1989;82(4):493-502.
The RFI des Comores is classified by WHO as an area where P. falciparum resistance to chloroquine is rare or low. After reviewing the existing data, the authors are giving the results of an in vivo research in 1988-1989. 1.35 of the tests with 25 mg/kg were positive the 7th day, 3.38% of 207 tests with 20 mg/kg, 10.77% of 232 tests with 10 mg/kg, 21.56% of 51 tests on 5 mg/kg.
科摩罗的恶性疟原虫对氯喹耐药性较低或罕见,被世界卫生组织列为该类地区。在审视现有数据后,作者给出了1988年至1989年的一项体内研究结果。25毫克/千克剂量的测试中,第7天有1.35%呈阳性;20毫克/千克剂量的207次测试中,有3.38%呈阳性;10毫克/千克剂量的232次测试中,有10.77%呈阳性;5毫克/千克剂量的51次测试中,有21.56%呈阳性。