Xu Feng, Li Ting, Xu Peng-Bo, Li Ling, Du Sha-Sha, Lian Hong-Li, Yang Hong-Quan
Key Laboratory of Urban Agriculture (South) Ministry of Agriculture and School of Agriculture and Biology, Shanghai Jiaotong University, China.
State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai, China.
FEBS Lett. 2016 Feb;590(4):541-9. doi: 10.1002/1873-3468.12076. Epub 2016 Feb 7.
Proper timing of flowering is essential for reproduction of plants. Although it is well known that both light and gibberellin (GA) signaling play critical roles in promoting flowering in Arabidopsis thaliana, whether and how they are integrated to regulate flowering remain largely unknown. Here, we show through biochemical studies that DELLA proteins physically interact with CONSTANS (CO). Furthermore, the interaction of CO with NF-YB2 is inhibited by the DELLA protein, RGA. Our findings suggest that regulation of flowering by GA signaling in leaves under long days is mediated, at least in part, through repression of DELLA proteins on CO, providing a molecular link between DELLA proteins, key components in GA signaling pathway, and CO, a critical flowering activator in photoperiod signaling pathway.
开花的恰当时间对植物繁殖至关重要。尽管众所周知光信号和赤霉素（GA）信号在促进拟南芥开花过程中都起着关键作用，但它们是否以及如何整合以调控开花在很大程度上仍不清楚。在此，我们通过生化研究表明，DELLA蛋白与CONSTANS（CO）存在物理相互作用。此外，DELLA蛋白RGA抑制了CO与NF - YB2的相互作用。我们的研究结果表明，长日照条件下叶片中GA信号对开花的调控至少部分是通过DELLA蛋白对CO的抑制来介导的，这在GA信号通路的关键成分DELLA蛋白与光周期信号通路中的关键开花激活因子CO之间建立了分子联系。
