糖尿病易感性的遗传学 - Suppr

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The genetics of susceptibility to diabetes.

作者信息

Wassmuth R, Lernmark A

机构信息

R. H. Williams Laboratory, Department of Medicine, University of Washington, Seattle 98195.

出版信息

Clin Immunol Immunopathol. 1989 Dec;53(3):358-99. doi: 10.1016/0090-1229(89)90002-0.

DOI:10.1016/0090-1229(89)90002-0

PMID:2680191

Abstract

摘要

相似文献

The genetics of susceptibility to diabetes.糖尿病易感性的遗传学

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Genetic markers in insulin-dependent (type I) diabetes mellitus.胰岛素依赖型（I型）糖尿病中的遗传标记

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Prediabetes in children: natural history, diagnosis, and preventive strategies.儿童糖尿病前期：自然史、诊断及预防策略

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The immunoglobulin heavy-chain variable region in insulin-dependent diabetes mellitus: affected-sib-pair analysis and association studies.胰岛素依赖型糖尿病中的免疫球蛋白重链可变区：受累同胞对分析及关联研究

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HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls.在基于人群的患病家庭和对照中所研究的I型（胰岛素依赖型）糖尿病中，HLA-DQ主要赋予保护作用，而HLA-DR则易导致发病。

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Inheritance of MHC class II genes in IDDM studied in population-based affected and control families.在基于人群的患病家庭和对照家庭中研究胰岛素依赖型糖尿病中MHC II类基因的遗传情况。

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Risk for developing type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies.患1型（胰岛素依赖型）糖尿病的风险及胰岛64K抗体的存在情况。

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DRB genotyping supports recessive inheritance of DR3-associated susceptibility to insulin-dependent diabetes mellitus.DRB基因分型支持与DR3相关的胰岛素依赖型糖尿病易感性的隐性遗传。

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Prevention of spontaneous and cyclophosphamide-induced diabetes in non-obese diabetic (NOD) mice with oral 2-acetyl-4-tetrahydroxybutylimidazole (THI), a component of caramel colouring III.使用焦糖色素III的一种成分——口服2-乙酰基-4-四羟基丁基咪唑（THI）预防非肥胖糖尿病（NOD）小鼠的自发性糖尿病和环磷酰胺诱导的糖尿病

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