Molecular analysis of the pathogenesis of beta-cell destruction in insulin-dependent diabetes mellitus.
作者信息
Lernmark A, Bärmeier H, Dube S, Hagopian W, Karlsen A E, Markholst H, Wilson C, Wassmuth R
机构信息
R. H. Williams Laboratory, Department of Medicine, University of Washington School of Medicine, Seattle 98195.
出版信息
West J Med. 1990 Nov;153(5):499-502.
Abstract
摘要
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Molecular analysis of the pathogenesis of beta-cell destruction in insulin-dependent diabetes mellitus.胰岛素依赖型糖尿病中β细胞破坏发病机制的分子分析
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本文引用的文献
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Abnormalities of immunoregulatory T cell subsets in patients with insulin-dependent diabetes mellitus.
J Immunol. 1982 Oct;129(4):1426-9.
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Pathologic anatomy of the pancreas in juvenile diabetes mellitus.青少年糖尿病患者胰腺的病理解剖
Diabetes. 1965 Oct;14(10):619-33. doi: 10.2337/diab.14.10.619.
3
Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans.亲和纯化的人白细胞介素I对分离的胰岛具有细胞毒性。
Diabetologia. 1986 Jan;29(1):63-7. doi: 10.1007/BF02427283.
4
A molecular basis for MHC class II--associated autoimmunity.MHC II类相关自身免疫的分子基础。
Science. 1988 May 20;240(4855):1003-9. doi: 10.1126/science.3368786.
5
Structure of the human class I histocompatibility antigen, HLA-A2.人类I类组织相容性抗原HLA - A2的结构
Nature. 1987;329(6139):506-12. doi: 10.1038/329506a0.
6
The BB rat.BB大鼠。
Diabetes Metab Rev. 1987 Jul;3(3):725-50. doi: 10.1002/dmr.5610030307.
7
The second International Workshop on the Standardisation of Insulin Autoantibody (IAA) measurement. Held in New York, 27-30 October 1987.
Diabetologia. 1988 Jul;31(7):449-50. doi: 10.1007/BF00271590.
8
Serum exchange and use of dilutions have improved precision of measurement of islet cell antibodies.
J Immunol Methods. 1988 Jan 21;106(1):83-8. doi: 10.1016/0022-1759(88)90274-8.
9
The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentration.白细胞介素1对大鼠胰腺β细胞的双峰效应——先刺激后抑制——取决于剂量、暴露持续时间和周围葡萄糖浓度。
Acta Endocrinol (Copenh). 1988 Oct;119(2):307-11. doi: 10.1530/acta.0.1190307.
10
Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis.HLA - DQ亚区域的特定基因组标记可区分DR4阳性的胰岛素依赖型糖尿病和DR4阳性的血清阳性青少年类风湿性关节炎。
J Exp Med. 1986 Jul 1;164(1):345-50. doi: 10.1084/jem.164.1.345.
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