Passler Jesse S, Clay Olivio J, Wadley Virginia G, Ovalle Fernando, Crowe Michael
Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA
Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.
J Geriatr Psychiatry Neurol. 2016 May;29(3):142-8. doi: 10.1177/0891988715627023. Epub 2016 Jan 21.
Self-reported stroke symptoms may represent unrecognized cerebrovascular events leading to poorer cognitive and mental health. We examined relationships between stroke symptoms, cognitive impairment, and depressive symptoms in a high-risk sample: 247 adults aged ≥65 with diabetes. Stroke symptoms were assessed using the Questionnaire for Verifying Stroke-free Status, cognitive impairment was measured with the modified Telephone Interview for Cognitive Status, and depressive symptoms were measured using the 15-item Geriatric Depression Scale. In 206 participants without history of stroke/transient ischemic attack, 27.7% reported stroke symptoms, with sudden loss of comprehension most frequently reported (11.7%). Having >1 versus 0 stroke symptoms was associated with greater odds of cognitive impairment (odds ratio = 3.04, 95% confidence interval 1.15-8.05) and more depressive symptoms (b= 2.60,P< .001) while controlling for age, race, gender, education, diabetes duration, diabetes severity, and cardiovascular comorbidities. Better recognition and treatment of cerebrovascular problems in older adults with diabetes may lead to improved cognition and mental health.
自我报告的中风症状可能代表未被识别的脑血管事件，这些事件会导致认知和心理健康状况较差。我们在一个高危样本中研究了中风症状、认知障碍和抑郁症状之间的关系：247名年龄≥65岁的糖尿病成年人。使用《无中风状态验证问卷》评估中风症状，用改良的《认知状态电话访谈》测量认知障碍，并用15项《老年抑郁量表》测量抑郁症状。在206名无中风/短暂性脑缺血发作病史的参与者中，27.7%报告有中风症状，其中最常报告的是突然丧失理解能力（11.7%）。在控制年龄、种族、性别、教育程度、糖尿病病程、糖尿病严重程度和心血管合并症的情况下，有1种及以上中风症状与认知障碍几率更高（优势比=3.04，95%置信区间1.15-8.05）以及更多抑郁症状（b=2.60，P<0.001）相关。更好地识别和治疗老年糖尿病患者的脑血管问题可能会改善认知和心理健康。
