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Notch 1 and Notch 2 synergistically regulate the differentiation and function of invariant NKT cells.
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Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling.
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Endogenous ligands of natural killer T cells are alpha-linked glycosylceramides.
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The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector differentiation.
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Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.
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The transcriptional programs of iNKT cells.
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Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation.
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Essential role for autophagy during invariant NKT cell development.
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Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue.
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