Ostertag-Hill Claire A, Abdo Ameen K, Alexander Jason Q, Skeik Nedaa
Minneapolis Heart Institute Research Foundation, Minneapolis, MN.
Vascular Surgery, Abbott Northwestern Hospital/Minneapolis Heart Institute, Minneapolis, MN.
Ann Vasc Surg. 2016 Apr;32:128.e7-13. doi: 10.1016/j.avsg.2015.10.021. Epub 2016 Jan 21.
Takayasu arteritis is a rare, chronic large vessel vasculitis of unknown etiology which predominantly affects women younger than 40 years of age. Symptoms are highly variable based on the location and extent of the stenosis, arterial occlusion, aneurysm, and thrombosis. Diagnosis is based on clinical presentation, relevant laboratory work-up, and imaging findings of wall thickening and stenosis of medium and large vessels. Management includes glucocorticoid therapy, frequently paired with adjunctive immunosuppressants, and sometimes surgical intervention in severe cases. Here, we present a unique case of Takayasu arteritis with critical distal aortic stenosis with very severe wall thickening involving the bilateral common iliac artery and leading to left iliac artery thrombosis. Based on our literature review, our article represents a very rare presentation of Takayasu arteritis with severe iliac artery thrombosis.
高安动脉炎是一种病因不明的罕见慢性大血管血管炎,主要影响40岁以下的女性。症状因狭窄、动脉闭塞、动脉瘤和血栓形成的部位及程度不同而有很大差异。诊断基于临床表现、相关实验室检查以及中大型血管壁增厚和狭窄的影像学表现。治疗包括糖皮质激素治疗,常联合辅助免疫抑制剂,严重病例有时需手术干预。在此,我们报告一例独特的高安动脉炎病例,其远端主动脉严重狭窄,双侧髂总动脉壁极度增厚,导致左髂动脉血栓形成。根据我们的文献综述,本文报道了高安动脉炎伴严重髂动脉血栓形成这一极为罕见的表现。