Terakawa Hirofumi, Kobayashi Takashi, Tokoro Tomokazu, Takeshita Masaki, Horikawa Naoki, Ohzawa Koji, Ozaki Kumi, Kobayashi Keiko, Terayama Noboru, Okada Eikichi, Yabushita Kazuhisa
Dept. of Surgery, Takaoka City Hospital.
Gan To Kagaku Ryoho. 2015 Nov;42(12):1836-8.
A 67-year-old man was treated for diabetes mellitus by his family doctor. A splenic tumor was suspected based on his pain in the left side of the abdomen. He was admitted to our hospital for close inspection and medical treatment. Abdominal CT and MRI scans showed a tumor, 10 cm in diameter, in the spleen. An opaque boundary with the diaphragm was also observed. On PET-CT, accumulations of FDG were observed in the left supraclavicular fossa and the left axilla. The serum levels of LDH and sIL-2R were elevated, and therefore a diagnosis of malignant lymphoma was suspected. Due to the risk of splenic rupture, a splenectomy was performed. After pathological examination, the patient was diagnosed with diffuse large B-cell malignant lymphoma. He is currently being treated with chemotherapy at another medical institute. Splenic rupture occurs in some cases of splenic malignant lymphoma, although the number of reported cases is low. In some of the cases, splenic rupture occurred during treatment of the malignant lymphoma. There is no specific way to measure the risk of splenic rupture; however, performing a prophylactic splenectomy is one option in cases where tumor cells have extended to the capsula lienis, similar to that in our patient.
一名67岁男性由其家庭医生治疗糖尿病。基于他左侧腹部疼痛怀疑有脾脏肿瘤。他被收治入我院进行仔细检查和治疗。腹部CT和MRI扫描显示脾脏有一个直径10厘米的肿瘤。还观察到与膈肌有不清晰的边界。在PET-CT上,左侧锁骨上窝和左腋窝观察到FDG聚集。血清LDH和sIL-2R水平升高,因此怀疑诊断为恶性淋巴瘤。由于有脾破裂风险,进行了脾切除术。病理检查后,患者被诊断为弥漫性大B细胞恶性淋巴瘤。他目前正在另一家医疗机构接受化疗。脾恶性淋巴瘤的某些病例会发生脾破裂,尽管报告的病例数较少。在一些病例中,脾破裂发生在恶性淋巴瘤治疗期间。没有测量脾破裂风险的特定方法;然而,在肿瘤细胞已扩展至脾包膜的情况下,如我们的患者,进行预防性脾切除术是一种选择。