Chang Jing, Chen Qing, Jian Yuan, Wei Ping, Yang Guang-Zhong, Wang Ying, Fang Xiang-Yang, Sun Qian-Mei
Department of Internal Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Gong-Ti South Road 8#, Chao-Yang District, Beijing, China.
Department of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Diagn Pathol. 2018 Aug 25;13(1):61. doi: 10.1186/s13000-018-0741-9.
Although the primary malignant spleen tumor is relatively rare, lymphoma is the most common splenic malignancy. It can have quite different clinical manifestations that usually lead to relatively poor outcomes, and thus early and accurate diagnosis are of utmost importance.
The present study reports a case of a 67-year-old female with high fever, abnormal spleen (diagnosed by PET/CT) and no obvious lymph node enlargement. After being subjected to splenectomy, the patient was diagnosed with splenic diffuse large B cell lymphoma coexisting with gastrointestinal stromal tumor in the stomach.
To our knowledge, splenic lymphoma accompanied by gastrointestinal stromal tumor in the stomach is rarely reported. This case report discusses the diagnosis and case management of a patient referring to the existing literature.
尽管原发性恶性脾脏肿瘤相对罕见，但淋巴瘤是最常见的脾脏恶性肿瘤。它可有 quite different 临床表现，通常导致相对较差的预后，因此早期准确诊断至关重要。
本研究报告一例67岁女性，有高热、脾脏异常（经PET/CT诊断）且无明显淋巴结肿大。脾切除术后，患者被诊断为脾脏弥漫性大B细胞淋巴瘤合并胃胃肠道间质瘤。
据我们所知，脾脏淋巴瘤合并胃胃肠道间质瘤鲜有报道。本病例报告参考现有文献讨论了一名患者的诊断及病例管理。
