Obermeyer Ziad, Clarke Alissa C, Makar Maggie, Schuur Jeremiah D, Cutler David M
Department of Emergency Medicine, School of Medicine, Harvard University, Boston, Massachusetts.
Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
J Am Geriatr Soc. 2016 Feb;64(2):323-9. doi: 10.1111/jgs.13948. Epub 2016 Jan 25.
To compare patterns of emergency department (ED) use and inpatient admission rates for elderly adults with cancer with a poor prognosis who enrolled in hospice to those of similar individuals who did not.
Matched case-control study.
Nationally representative sample of Medicare fee-for-service beneficiaries with cancer with a poor prognosis who died in 2011.
Beneficiaries in hospice matched to individuals not in hospice on time from diagnosis of cancer with a poor prognosis to death, region, age, and sex.
Comparison of ED use and inpatient admission rates before and after hospice enrollment for beneficiaries in hospice and controls.
Of 272,832 matched beneficiaries, 81% visited the ED in the last 6 months of life. At baseline, daily ED use and admission rates were not significantly different between beneficiaries in and not in hospice. By the week before death, nonhospice controls averaged 69.6 ED visits/1,000 beneficiary-days, versus 7.6 for beneficiaries in hospice (rate ratio (RR) = 9.7, 95% confidence interval (CI) = 9.3-10.0). Inpatient admission rates in the last week of life were 63% for nonhospice controls and 42% for beneficiaries in hospice (RR = 1.51, 95% CI = 1.45-1.57). Of all beneficiaries in hospice, 28% enrolled during inpatient stays originating in EDs; they accounted for 35.7% (95% CI = 35.4-36.0%) of all hospice stays of less than 1 month and 13.9% (95% CI = 13.6-14.2%) of stays longer than 1 month.
Most Medicare beneficiaries with cancer with a poor prognosis visited EDs at the end of life. Hospice enrollment was associated with lower ED use and admission rates. Many individuals enrolled in hospice during inpatient stays that followed ED visits, a phenomenon linked to shorter hospice stays. These findings must be interpreted carefully given potential unmeasured confounders in matching.
比较加入临终关怀的预后较差的老年癌症患者与未加入临终关怀的类似个体的急诊科(ED)使用模式和住院率。
配对病例对照研究。
2011年死亡的具有全国代表性的医疗保险按服务收费的预后较差的癌症受益样本。
从癌症预后较差的诊断到死亡的时间、地区、年龄和性别方面,加入临终关怀的受益人与未加入临终关怀的个体进行匹配。
比较加入临终关怀的受益人和对照组在加入临终关怀前后的急诊科使用情况和住院率。
在272,832名匹配的受益人中,81%在生命的最后6个月内去过急诊科。在基线时,加入临终关怀和未加入临终关怀的受益人之间的每日急诊科使用情况和住院率没有显著差异。到死亡前一周,未加入临终关怀的对照组平均每1000受益人日有69.6次急诊科就诊,而加入临终关怀的受益人为7.6次(率比(RR)=9.7,95%置信区间(CI)=9.3-10.0)。生命最后一周的住院率,未加入临终关怀的对照组为63%,加入临终关怀的受益人为42%(RR = 1.51,95% CI = 1.45-1.57)。在所有加入临终关怀的受益人中,28%是在因急诊科就诊而住院期间加入的;他们占所有少于1个月的临终关怀住院的35.7%(95% CI = 35.4-36.0%)和超过1个月住院的13.9%(95% CI = 13.6-14.2%)。
大多数预后较差的医疗保险癌症受益人在生命末期去过急诊科。加入临终关怀与较低的急诊科使用和住院率相关。许多人在急诊科就诊后的住院期间加入了临终关怀,这一现象与较短的临终关怀住院时间有关。考虑到匹配中潜在的未测量混杂因素,这些发现必须谨慎解释。