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哺乳动物的松果体褪黑素:四季的时钟。

Mammalian pineal melatonin: a clock for all seasons.

作者信息

Bartness T J, Goldman B D

机构信息

Department of Psychology, Georgia State University, Atlanta 30303.

出版信息

Experientia. 1989 Oct 15;45(10):939-45. doi: 10.1007/BF01953051.

DOI:10.1007/BF01953051
PMID:2680574
Abstract

The central role of the pineal gland and its hormone melatonin (MEL) in mammalian photoperiodic responses is discussed in terms of: 1) evidence for the involvement of MEL in photoperiodism, 2) which feature of the MEL secretion profile might be most important for regulating photoperiodic responses, 3) evidence for the modulation of responses to changes in daylength based on previous photoperiod exposure (i.e., photoperiodic history) and 4) how the MEL signal might be processed at its target sites to elicit physiological responses.

摘要

松果体及其激素褪黑素(MEL)在哺乳动物光周期反应中的核心作用将从以下几个方面进行讨论:1)褪黑素参与光周期现象的证据;2)褪黑素分泌模式的哪些特征可能对调节光周期反应最为重要;3)基于先前光周期暴露(即光周期历史)对日照长度变化的反应调节的证据;4)褪黑素信号在其靶位点如何被处理以引发生理反应。

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Pineal melatonin content in male hamsters throughout the seasonal reproductive cycle.雄性仓鼠在季节性繁殖周期中松果体褪黑素含量。
Proc Soc Exp Biol Med. 1980 Nov;165(2):330-4. doi: 10.3181/00379727-165-40981.
2
Melatonin: identification of sites of antigonadal action in mouse brain.褪黑素:小鼠大脑中抗性腺作用位点的鉴定
Science. 1981 Nov 13;214(4522):821-3. doi: 10.1126/science.7292016.
3
Photoperiodic termination of hamster refractoriness: participation of the pineal gland.仓鼠不应期的光周期终止:松果体的参与。
季节性变化下丘脑甲状腺激素系统在不同冬季表型的达乌尔黄鼠(Phodopus sungorus)。
PLoS One. 2024 Oct 25;19(10):e0309591. doi: 10.1371/journal.pone.0309591. eCollection 2024.
4
The Effects of STRA6 Regulation of the Circadian Rhythm on Choroidal Neovascularization.STRA6 调控生物钟节律对脉络膜新生血管的影响。
Invest Ophthalmol Vis Sci. 2024 Sep 3;65(11):21. doi: 10.1167/iovs.65.11.21.
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One Health: Circadian Medicine Benefits Both Non-human Animals and Humans Alike.One Health:昼夜节律医学使非人类动物和人类受益。
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R Soc Open Sci. 2023 Mar 29;10(3):221436. doi: 10.1098/rsos.221436. eCollection 2023 Mar.
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