Zamost'ianova G B, Urakov A L
Farmakol Toksikol. 1989 Jul-Aug;52(4):27-9.
In experiments with total ischemia of the isolated rat heart it was found that a preliminary administration of preparations with malonate-like action to the animals exerts, unlike isoptin, cold-like effect on the time-course of calcium levels in mitochondria of the ischemic myocardium and limits the process of accumulation and release of calcium by organelles.
在对离体大鼠心脏进行完全缺血的实验中发现,与异搏定不同,预先给动物施用具有丙二酸酯样作用的制剂,对缺血心肌线粒体中钙水平的时间进程产生类似冷的效应,并限制细胞器对钙的积累和释放过程。