Chen Y A, Rivera-Serrano C M, Chen C, Chen Y R
Craniofacial Centre, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Craniofacial Research Centre, Chang Gung Memorial Hospital, Linkou, Taiwan.
Department of Anaesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Int J Oral Maxillofac Surg. 2016 Jun;45(6):783-6. doi: 10.1016/j.ijom.2015.09.014. Epub 2016 Jan 20.
In orthognathic surgery, maxillary (CNV2) and mandibular (CNV3) divisions of the trigeminal nerve can be blocked successfully prior to surgery. In this study, it was hypothesized that regional blocks (nerve block over a particular region: bilateral CNV2 and CNV3 divisions of the trigeminal nerve) would decrease the total requirement for intraoperative anaesthetic agents and facilitate the process of hypotensive anaesthesia. Local anaesthesia containing 1/100,000 epinephrine and 10ml 0.5% levobupivacaine was injected into the planned incisions in 50 patients. Twenty-five patients (group A) underwent orthognathic surgery without regional blocks and another 25 patients (group B) underwent surgery with regional blocks. The anaesthetic protocol was the same in both groups and administered by a single anaesthesiologist. The mean arterial pressure was recorded at several points throughout the operation, as well as all the medications used. The blood loss and the amounts of medications administered were lower in group B than in group A. In patients receiving regional blocks, the amounts of fentanyl and nicardipine required were significantly lower. The use of pre-emptive anaesthesia in orthognathic surgery may reduce the overall amounts of medications required for hypotensive anaesthesia, facilitate the intraoperative control of blood pressure, and decrease intraoperative blood loss.
在正颌外科手术中,三叉神经的上颌支(CNV2)和下颌支(CNV3)可在手术前成功阻滞。在本研究中,假设区域阻滞(特定区域的神经阻滞:三叉神经双侧CNV2和CNV3分支)会降低术中麻醉剂的总需求量,并有助于低血压麻醉过程。将含有1/100,000肾上腺素和10ml 0.5%左旋布比卡因的局部麻醉剂注入50例患者的计划切口处。25例患者(A组)未进行区域阻滞接受正颌外科手术,另外25例患者(B组)进行区域阻滞接受手术。两组的麻醉方案相同,由同一名麻醉医生实施。在整个手术过程中的几个时间点记录平均动脉压以及所有使用的药物。B组的失血量和药物使用量均低于A组。接受区域阻滞的患者所需的芬太尼和尼卡地平量显著更低。在正颌外科手术中使用超前麻醉可能会减少低血压麻醉所需的药物总量,便于术中血压控制,并减少术中失血量。