Łabuś Wojciech, Kawecki Marek, Glik Justyna, Maj Mariusz, Kitala Diana, Misiuga Marcelina, Klama-Baryła Agnieszka, Kraut Małgorzata, Nowak Mariusz
Pol Przegl Chir. 2015 Oct;87(10):513-21. doi: 10.1515/pjs-2015-0097.
As a result of the removal of cells from human allogeneic dermis, a collagen scaffold is obtained, which can be populated de novo with autologous/allogeneic skin cells and transplanted onto the area of skin loss. The optimal method for production of acellular dermal matrices (ADM) has been selected. Three female patients (a mean age of 54 years) were subjected to the transplantation of either autologous or allogeneic keratinocytes and fibroblasts into the holes of acellular dermal matrix (ADM) mesh graft. The method for burn wound treatment based on the use of a viable dermal-epidermal skin substitute (based on ADM and in vitro cultured fibroblasts and keratinocytes) may be the optimal method of burn treatment.
通过从人异体真皮中去除细胞，可获得一种胶原支架，该支架可重新接种自体/异体皮肤细胞并移植到皮肤缺损区域。已选择了生产脱细胞真皮基质（ADM）的最佳方法。三名女性患者（平均年龄54岁）接受了将自体或异体角质形成细胞和成纤维细胞移植到脱细胞真皮基质（ADM）网状移植物的孔中的治疗。基于使用有活力的真皮 - 表皮皮肤替代物（基于ADM以及体外培养的成纤维细胞和角质形成细胞）的烧伤创面治疗方法可能是烧伤治疗的最佳方法。
