Dilek Ömer F, Sevim Kamuran Z, Dilek Osman N
Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul 34396, Türkiye.
Department of Plastic and Reconstructive Surgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul 34396, Türkiye.
World J Clin Cases. 2024 Dec 16;12(35):6791-6807. doi: 10.12998/wjcc.v12.i35.6791.
Large-scale defects of body in the reconstructive surgical practice, and the helplessness of their repair with autologous tissues, have been an important factor in the development of artificial biological products for the temporary, definitive, or staged repair of these defects. A major advance in the field of plastic and other reconstructive surgery in this regard has been the introduction and successful use of acellular dermal matrices (ADMs). In recent years, not only the type of tissue from which ADMs are produced, product range, diversity and areas of use have increased, but their use in reconstructive fields, especially in post oncologic breast surgery, has become highly regarded and this has favored ADMs to be a potential cornerstone in specific and well-defined surgical fields in future. It is essential that reconstructive surgeons become familiar with some of the ADM's as well as the advantages and limitations to their use. This review not only provides basic science and clinical evidence of the current use of ADMs in wide range of surgical fields but also targets to keep them as an important backdrop in the armamentarium of reconstructive surgeons. Brief considerations of possible future directions for ADMs are also conducted in the end.
在重建外科实践中，身体的大面积缺损以及使用自体组织修复这些缺损时的无奈，一直是开发用于临时、确定性或分期修复这些缺损的人工生物制品的一个重要因素。在这方面，整形及其他重建外科领域的一项重大进展是无细胞真皮基质（ADM）的引入和成功应用。近年来，不仅生产ADM的组织类型、产品范围、多样性和使用领域有所增加，而且它们在重建领域，尤其是肿瘤后乳房手术中的应用受到高度重视，这使得ADM有望成为未来特定且明确的外科领域的潜在基石。重建外科医生必须熟悉一些ADM及其使用的优缺点。本综述不仅提供了ADM在广泛外科领域当前应用的基础科学和临床证据，还旨在将其作为重建外科医生工具库中的重要背景知识。最后还简要探讨了ADM未来可能的发展方向。
