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用于重建手术的人脱细胞真皮基质——综述

Human Acellular Dermal Matrix in Reconstructive Surgery-A Review.

作者信息

Gierek Marcin, Łabuś Wojciech, Kitala Diana, Lorek Andrzej, Ochała-Gierek Gabriela, Zagórska Karolina Mikuś, Waniczek Dariusz, Szyluk Karol, Niemiec Paweł

机构信息

Dr Stanislaw Sakiel Burn Treatment Centre in Siemianowice Slaskie, 41-100 Siemianowice Slaskie, Poland.

Department of Surgical Oncology, University Medical Center, Silesian Medical University, ul. Ceglana 35, 40-514 Katowice, Poland.

出版信息

Biomedicines. 2022 Nov 9;10(11):2870. doi: 10.3390/biomedicines10112870.

Abstract

Reconstructive surgery often confronts large tissue defects. This creates a need to look for materials that are immunogenic but offer the possibility of tissue filling. ADM-acellular dermal matrix-is a biological collagen matrix without immunogenicity, which is more commonly used in surgical treatment. Reconstructive surgery is still searching for various biocompatible materials that can be widely used in surgery. The available materials have their advantages and disadvantages. This paper is a literature review on the use of human acellular dermal matrix (ADM) in reconstructive surgery (surgical oncology, plastic and reconstructive surgery, and gynecologic reconstructive surgery). ADM appears to be a material of increasing use in various fields of surgery, and thus, further research in this area is required.

摘要

重建手术常常面临大面积组织缺损的情况。这就需要寻找具有免疫原性但又具备组织填充可能性的材料。脱细胞真皮基质(ADM)是一种无免疫原性的生物胶原基质,在外科治疗中应用更为普遍。重建手术仍在探寻各种可广泛应用于外科手术的生物相容性材料。现有的材料都各有优缺点。本文是一篇关于人脱细胞真皮基质(ADM)在重建手术(外科肿瘤学、整形与重建外科以及妇科重建外科)中应用的文献综述。ADM似乎是一种在各个外科领域使用日益增多的材料,因此,这一领域需要进一步开展研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd24/9687949/3fc708fd44c0/biomedicines-10-02870-g001.jpg

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