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子宫腺肌病患者在接受促性腺激素释放激素激动剂(GnRHa)和孕激素治疗后自然受孕。

Spontaneous conception following GnRHa and progestogen therapy in adenomyosis.

作者信息

Dasrilsyah Rima Anggrena, Shan Lim Pei, Kwang Ng Beng, Shafiee Mohamad Nasir, Omar Mohd Hashim

出版信息

Horm Mol Biol Clin Investig. 2016 Aug 1;27(2):77-9. doi: 10.1515/hmbci-2015-0061.

Abstract

Adenomyosis is a common gynaecological disorder that is associated with infertility and miscarriage. We report a case of adenomyosis presented with urinary retention and infertility. The patient successfully conceived spontaneously following GnRHa followed by progestogen therapy. This treatment option might provide a synergistic effect in improving fertility and pregnancy outcome for women with adenomyosis. This modality has no potential surgical risk; it minimises the long-term side effects of GnRHa and also provides luteal support.

摘要

子宫腺肌病是一种常见的妇科疾病,与不孕和流产有关。我们报告一例子宫腺肌病患者,表现为尿潴留和不孕。该患者在接受促性腺激素释放激素激动剂(GnRHa)治疗后,接着使用孕激素治疗,成功自然受孕。这种治疗方案可能对改善子宫腺肌病女性的生育能力和妊娠结局具有协同作用。这种治疗方式没有潜在的手术风险;它能将GnRHa的长期副作用降至最低,还能提供黄体支持。

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