Han Lei, Liu Yanni, Lao Kaixue, Jiang Jianxi, Zhang Caiying, Wang Yanlin
Department of Reproductive Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Department of Reproductive Medicine, Maternal and Child Health Hospital Affiliated to Zunyi Medical University, Zunyi, Binzhou, China.
Front Med (Lausanne). 2023 Mar 30;10:1133042. doi: 10.3389/fmed.2023.1133042. eCollection 2023.
Adenomyosis is a diffuse or localized organic disease caused by benign invasion of endometrial glands and stroma into the myometrium. It is a common disease that seriously affects reproductive health of women in childbearing age. Due to the unknown etiology and pathophysiological mechanism, and the lack of unified diagnostic criteria and effective treatment methods, total or subtotal hysterectomy has become a radical treatment for adenomyosis, which will lead to the complete loss of fertility. With the continuous exploration of the treatment to adenomyotic patients who have infertility or fertility intentions, new drugs, surgical methods and treating concepts appears. Adopt individualized conservative therapeutic strategies for patients with different conditions, preserve the uterus as much as possible and protect the patient's fertility, which will play an important role on the follow-up assisted reproductive treatment and long-term management of adenomyosis.
子宫腺肌病是一种由子宫内膜腺体和间质良性侵入子宫肌层引起的弥漫性或局限性器质性疾病。它是一种常见疾病，严重影响育龄期女性的生殖健康。由于病因和病理生理机制不明，且缺乏统一的诊断标准和有效的治疗方法，全子宫切除术或次全子宫切除术已成为子宫腺肌病的根治性治疗方法，这将导致生育能力完全丧失。随着对有不孕或生育意愿的子宫腺肌病患者治疗方法探索不断深入，新的药物、手术方法和治疗理念不断涌现。针对不同病情的患者采取个体化的保守治疗策略，尽可能保留子宫并保护患者的生育能力，这对后续的辅助生殖治疗及子宫腺肌病长期管理具有重要意义。
