一例淋巴瘤样丘疹病与霍奇金病。

A case of lymphomatoid papulosis and Hodgkin's disease.

作者信息

Pinto G M, Gonçalves L, Gonçalves H, Graça F, Quental A, Fonseca I, Monteiro A

机构信息

Department of Dermatology, Curry Cabral Hospital, Lisboa, Portugal.

出版信息

J Am Acad Dermatol. 1989 Nov;21(5 Pt 2):1051-6. doi: 10.1016/s0190-9622(89)70294-2.

DOI:10.1016/s0190-9622(89)70294-2

PMID:2681291

Abstract

Lymphomatoid papulosis is a unique paradoxic entity characterized by recurrent self-healing papulonodular lesions with histologic features of malignancy. Usually the disease has a protracted benign course; however, it can be associated with or evolve to a lymphoproliferative disorder. Thus "lymphoma-associated papulosis" represents the malignant end of a wide spectrum. We describe a case of a patient with lymphomatoid papulosis who developed Hodgkin's disease 8 years after the onset of skin lesions. Systemic chemotherapy achieved complete remission of Hodgkin's disease, but recurrent papulonodular lesions continued to form in the subsequent 18 months.

摘要

淋巴瘤样丘疹病是一种独特的矛盾性疾病，其特征为具有恶性组织学特征的反复自愈性丘疹结节性皮损。通常该疾病病程呈良性且迁延；然而，它可能与淋巴增殖性疾病相关或演变为淋巴增殖性疾病。因此，“淋巴瘤相关丘疹病”代表了广泛谱系中的恶性末端。我们描述了一例淋巴瘤样丘疹病患者，其在皮肤病变出现8年后发生了霍奇金病。全身化疗使霍奇金病完全缓解，但在随后的18个月里仍不断出现丘疹结节性皮损。