Chen K T, Flam M S
Am J Dermatopathol. 1985 Dec;7(6):555-61. doi: 10.1097/00000372-198512000-00010.
A patient with a 14-year history of lymphomatoid papulosis developed localized subcutaneous lymphoma with morphologic features of Hodgkin's disease at the age of 46 years. The lymphoma was clinically atypical in that it remained localized in the subcutis for 10 years before involvement of lymph nodes occurred. A review of the literature indicates that patients with lymphomatoid papulosis, especially those with plaque or nodular lesions in addition to papular lesions, are given to develop malignant lymphomas of various histologic types.
一名患有淋巴瘤样丘疹病14年的患者在46岁时发展为具有霍奇金病形态学特征的局限性皮下淋巴瘤。该淋巴瘤在临床上不典型,因为在淋巴结受累之前,它在皮下组织局限存在了10年。文献回顾表明,淋巴瘤样丘疹病患者,尤其是除丘疹性病变外还有斑块或结节性病变的患者,容易发展为各种组织学类型的恶性淋巴瘤。