[高海拔地区藏族与长期居住汉族青年男性睡眠结构及质量差异的初步研究]

[Pilot study on the differences of young male's sleep structure and quality between indigenous Tibetans and longtime Han residents in high altitude area].

作者信息

Li Yuhong, Gao Lu, Wuren Tana, Ga Qin, Guan Wei, Ge Rili

机构信息

Department of Respiratory Medicine, Affiliated Hospital of Qinghai University, Xining 810001, China.

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2015 Nov 10;95(42):3416-9.

PMID:26813129

Abstract

OBJECTIVE

To compare young males' sleep quality and structure between native Tibetans and longtime Han residents.

METHODS

A total of 14 male Tibetans and 11 male Hans at an altitude of 3 780 m were enrolled in this study. Tibetans were native highlanders with a mean age of (32.0 ± 9.1) years. Han subjects were born and living in high altitude with a mean age of (36.6 ± 7.6) years. All subjects were monitored by Polysomnography(PSG), and the differences of sleep structure and quality between the two groups were compared according to the international standard.

RESULTS

The sleep efficiency (93.1% ± 3.9% vs 85.7% ± 4.2%) and nocturnal oxygen saturation (SpO(2)) (89.4% ± 2.0% vs 84.6% ± 4.3%) in Tibetans was significantly higher than those in Hans (both P<0.05). The number of awakening ((1.9 ± 0.8) vs (4.1 ± 1.3)/h) and micro-awakening ((23.4 ± 5.8) vs (28.7 ± 4.1)/h), the oxygen reduction index ((11.7 ± 4.8) vs (16.3 ± 7.5)/h), apnea hypoventilation index (AHI) ((5.8 ± 2.3) vs (9.6 ± 4.2)/h) and average heart rate ((66.9 ± 8.3) vs (79.9 ± 6.7)/min) of Tibetans were significantly lower than Hans (all P<0.05). Tibetans had longer slow wave sleep (20.1% ± 7.2% vs 8.8% ± 3.3%) and the Hans had longer stage 2 of non-rapid eye movement (NREM) (31.1% ± 11.9% vs 18.4% ± 6.7%) and shallow sleep (76.1 ± 11.7 vs 70.8 ± 11.2) (all P<0.05).

CONCLUSION

Tibetans have better sleep quality and higher sleep efficiency than Han residents at high altitude.

摘要

目的

比较藏族和长期居住在当地的汉族年轻男性的睡眠质量和结构。

方法

本研究纳入了14名居住在海拔3780米的藏族男性和11名汉族男性。藏族为本地高原居民，平均年龄为（32.0±9.1）岁。汉族受试者在高原出生并生活，平均年龄为（36.6±7.6）岁。所有受试者均接受多导睡眠图（PSG）监测，并根据国际标准比较两组之间睡眠结构和质量的差异。

结果

藏族的睡眠效率（93.1%±3.9%对85.7%±4.2%）和夜间血氧饱和度（SpO₂）（89.4%±2.0%对84.6%±4.3%）显著高于汉族（均P<0.05）。藏族的觉醒次数（（1.9±0.8）对（4.1±1.3）/小时）和微觉醒次数（（23.4±5.8）对（28.7±4.1）/小时）、氧减指数（（11.7±4.8）对（16.3±7.5）/小时）、呼吸暂停低通气指数（AHI）（（5.8±2.3）对（9.6±4.2）/小时）和平均心率（（66.9±8.3）对（79.9±6.7）/分钟）均显著低于汉族（均P<0.05）。藏族的慢波睡眠时间更长（20.1%±7.2%对8.8%±3.3%），而汉族的非快速眼动（NREM）睡眠2期更长（31.1%±11.9%对18.4%±6.7%），浅睡眠时间更长（76.1±11.7对70.8±11.2）（均P<0.05）。