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改善男男性行为者暴露前预防措施在门诊的实施情况。

Improving outpatient implementation of preexposure prophylaxis in men who have sex with men.

作者信息

Scholl Elizabeth

机构信息

University of Pennsylvania.

出版信息

J Am Assoc Nurse Pract. 2016 Aug;28(8):446-52. doi: 10.1002/2327-6924.12344. Epub 2016 Jan 27.

Abstract

BACKGROUND AND PURPOSE

Preexposure prophylaxis (PrEP) has been shown to decrease the transmission of human immunodeficiency virus (HIV) when used in high-risk populations including men who have sex with men. However, despite effectiveness, there is underutilization in the outpatient setting. This review aims to assess the facilitators and barriers to improve outpatient utilization.

METHODS

A systematic search of four databases, CINAHL, Ovid, Scopus, and PsychINFO, during March-May of 2015. A total of 22 articles were included for review.

CONCLUSIONS

Barriers to utilization were either patient or provider centered. Patient barriers included a significant lack of knowledge, stigma, risk-taking, and adherence. Provider barriers also included lack of knowledge of treatment and protocols as well as fears of resistance and behavior change. Facilitators included adherence regimens, education, and comprehensive care.

IMPLICATIONS FOR PRACTICE

Men who have sex with men are a high-risk population for HIV transmission. PrEP is successful in this subgroup at reducing transmission. Through education, nonjudgmental and comprehensive care providers can utilize PrEP to decrease transmission.

摘要

背景与目的

暴露前预防(PrEP)已被证明在包括男男性行为者在内的高危人群中使用时可降低人类免疫缺陷病毒(HIV)的传播。然而,尽管有效,但在门诊环境中其使用率仍较低。本综述旨在评估促进门诊使用PrEP的因素和障碍。

方法

于2015年3月至5月对四个数据库(CINAHL、Ovid、Scopus和PsychINFO)进行系统检索。共纳入22篇文章进行综述。

结论

使用PrEP的障碍要么以患者为中心,要么以提供者为中心。患者方面的障碍包括严重缺乏知识、耻辱感、冒险行为和依从性问题。提供者方面的障碍还包括对治疗和方案缺乏了解以及对耐药性和行为改变的担忧。促进因素包括依从性方案、教育和综合护理。

对实践的启示

男男性行为者是HIV传播的高危人群。PrEP在该亚组中成功降低了传播率。通过教育,无偏见且提供综合护理的提供者可以利用PrEP来减少传播。

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