Kang Taekhyun, Kim Hyung Ook, Kim Hungdai, Chun Ho-Kyung, Han Won Kon, Jung Kyung Uk
Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University of School of Medicine, Seoul, Korea.
Ann Coloproctol. 2015 Dec;31(6):228-34. doi: 10.3393/ac.2015.31.6.228. Epub 2015 Dec 31.
With extended life expectancy, the mean age of patients at the time of diagnosis of colorectal cancer and its treatment, including radical resection, is increasing gradually. We aimed to evaluate the impact of age on postoperative clinical outcomes after a laparoscopic resection of colorectal cancers.
This is a retrospective review of prospectively collected data. Patients with primary colorectal malignancies or premalignant lesions who underwent laparoscopic colectomies between January 2009 and April 2013 were identified. Patients were divided into 6 groups by age using 70, 75, and 80 years as cutoffs: younger than 70, 70 or older, younger than 75, 75 or older, younger than 80, and 80 or older. Demographics, pathological parameters, and postoperative clinical outcomes, including postoperative morbidity, were compared between the younger and the older age groups.
All 578 patients underwent a laparoscopic colorectal resection. The overall postoperative complication rate was 21.1% (n = 122). There were 4 cases of operative mortality (0.7%). Postoperative complication rates were consistently higher in the older groups at all three cutoffs; however, only the comparison with a cutoff at 80 years showed a statistically significant difference between the younger and the older groups.
Age over 80 is a possible risk factor for postoperative morbidity after a laparoscopic resection of colorectal cancer.
随着预期寿命的延长,包括根治性切除在内的结直肠癌诊断及治疗时患者的平均年龄在逐渐增加。我们旨在评估年龄对腹腔镜结直肠癌切除术后临床结局的影响。
这是一项对前瞻性收集数据的回顾性研究。确定2009年1月至2013年4月期间接受腹腔镜结肠切除术的原发性结直肠恶性肿瘤或癌前病变患者。以70岁、75岁和80岁为界将患者按年龄分为6组:小于70岁、70岁及以上、小于75岁、75岁及以上、小于80岁、80岁及以上。比较年轻和老年年龄组之间的人口统计学、病理参数及术后临床结局,包括术后发病率。
所有578例患者均接受了腹腔镜结直肠癌切除术。总体术后并发症发生率为21.1%(n = 122)。有4例手术死亡(0.7%)。在所有三个分界点上,老年组的术后并发症发生率始终较高;然而,只有与80岁分界点的比较显示年轻组和老年组之间存在统计学显著差异。
80岁以上是腹腔镜结直肠癌切除术后发生术后并发症的一个可能危险因素。