Múgica-García M V, Tejedor-Alonso M A, Moro-Moro M, Esteban-Hernández J, Rojas-Perez-Ezquerra P E, Vila-Albelda C, Rosado-Ingelmo A
J Investig Allergol Clin Immunol. 2015;25(6):408-15.
Our objective was to ascertain the degree of adherence to recommendations made to patients with anaphylaxis, most of whom were attended in our allergy outpatient clinic.
A questionnaire was sent to 1512 patients who had experienced anaphylaxis and completed by 887. The chosen definition of anaphylaxis was that of the National Institute of Allergy and Infectious Diseases and the Food Allergy and Anaphylaxis Network Symposium. We evaluated the prescription, purchase, and use of epinephrine auto-injectors and oral drugs, as well as the avoidance of allergens involved in previous anaphylaxis episodes.
Most patients (94.53%) reported that they had received advice on avoidance of responsible allergens after their allergy workup. Epinephrine auto-injectors and oral drugs were prescribed according to the subtype of anaphylaxis. Only 30.74% of patients used the epinephrine auto-injector; 54.26% took oral medication. Most patients (88.3%) avoided the allergen.
Despite general agreement that anaphylaxis occurring in the community should be treated with epinephrine auto-injectors, use of these devices to treat recurrences was low in our patients. Oral medication intake was more common than the epinephrine auto-injector in all subtypes. In order to increase adherence to epinephrine auto-injectors, it is necessary to think beyond the measures recommended during regular visits to allergy outpatient clinics.
我们的目标是确定对过敏反应患者所提建议的遵守程度，其中大多数患者在我们的过敏门诊就诊。
向1512名有过过敏反应的患者发送了问卷，887名患者完成了问卷。所采用的过敏反应定义来自美国国立过敏和传染病研究所及食物过敏与过敏反应网络研讨会。我们评估了肾上腺素自动注射器和口服药物的处方、购买及使用情况，以及对先前过敏反应发作中涉及的过敏原的规避情况。
大多数患者（94.53%）报告称，在其过敏检查后，他们已收到关于规避相关过敏原的建议。根据过敏反应的亚型开具了肾上腺素自动注射器和口服药物。只有30.74%的患者使用了肾上腺素自动注射器；54.26%的患者服用了口服药物。大多数患者（88.3%）规避了过敏原。
尽管普遍认为社区发生的过敏反应应以肾上腺素自动注射器治疗，但在我们的患者中，使用这些设备治疗复发情况的比例较低。在所有亚型中，口服药物的服用比肾上腺素自动注射器更常见。为了提高对肾上腺素自动注射器的依从性，有必要超越在过敏门诊定期就诊时所建议的措施进行思考。
