Ripa L W
Department of Children's Dentistry, School of Dental Medicine, State University of New York, Stony Brook 11794-8701.
J Public Health Dent. 1989;49(5 Spec No):297-309. doi: 10.1111/j.1752-7325.1989.tb02088.x.
Of the five types of topical fluoride gel products available in the United States, two have not been clinically tested in randomized double blind clinical trials. For those tested, the averaged results of clinical trials involving schoolchildren in fluoride-deficient communities indicate a caries reduction of approximately 26 percent from either a professional or self-administered program. A similar relative reduction can be expected from programs conducted in fluoridated communities, but the absolute caries inhibition is less. Twice-a-year professional applications are more effective than once-a-year applications, and self-applications using trays are more effective than applying the gel on a toothbrush. For subjects beyond school age, there are few clinical studies of either self-applied or professionally applied gels; however, current epidemiological evidence does not indicate a need for public health caries preventive programs for healthy employed adults. For medically compromised patients, especially those exhibiting rampant caries associated with radiation-induced xerostomia, a variety of topical gel procedures appear to be effective in limiting caries.
在美国现有的五种局部用氟凝胶产品中，有两种尚未在随机双盲临床试验中进行临床测试。对于经过测试的产品，在缺氟社区对学童进行的临床试验平均结果表明，无论是专业应用还是自我应用方案，龋齿减少约26%。在氟化社区开展的项目预计也会有类似的相对减少，但绝对防龋效果较小。每年进行两次专业应用比每年进行一次更有效，使用托盘进行自我应用比在牙刷上涂抹凝胶更有效。对于学龄以上的人群，关于自我应用或专业应用凝胶的临床研究很少；然而，目前的流行病学证据并不表明健康的在职成年人需要公共卫生防龋项目。对于有医学问题的患者，尤其是那些患有与放射性口干相关的猖獗性龋齿的患者，各种局部凝胶程序似乎在限制龋齿方面是有效的。
