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APOL1 Variants: From Parasites to Kidney Function to Cardiovascular Disease.

作者信息

Reiner Alex P, Susztak Katalin

机构信息

From the Fred Hutchinson Cancer Research Center, WHI Clinical Coordinating Center/Public Health Sciences (A.P.R.), and Renal Electrolyte and Hypertension Division, Department of Medicine, Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (K.S.).

出版信息

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):219-20. doi: 10.1161/ATVBAHA.115.306794.

DOI:10.1161/ATVBAHA.115.306794
PMID:26819463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4732577/
Abstract
摘要

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Mol Ther. 2022 Jul 6;30(7):2491-2504. doi: 10.1016/j.ymthe.2022.04.007. Epub 2022 Apr 20.
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ApoL1 and the Immune Response of Patients with Systemic Lupus Erythematosus.载脂蛋白L1与系统性红斑狼疮患者的免疫反应
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本文引用的文献

1
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.一项基于千人基因组计划的冠心病全基因组关联荟萃分析。
Nat Genet. 2015 Oct;47(10):1121-1130. doi: 10.1038/ng.3396. Epub 2015 Sep 7.
2
APOL1 Kidney Disease Risk Variants: An Evolving Landscape.载脂蛋白L1肾病风险变异体：不断演变的格局
Semin Nephrol. 2015 May;35(3):222-36. doi: 10.1016/j.semnephrol.2015.04.008.
3
HIV-associated nephropathies: epidemiology, pathology, mechanisms and treatment.HIV 相关性肾病：流行病学、病理学、发病机制与治疗。
Nat Rev Nephrol. 2015 Mar;11(3):150-60. doi: 10.1038/nrneph.2015.9. Epub 2015 Feb 17.
4
Functional genomic annotation of genetic risk loci highlights inflammation and epithelial biology networks in CKD.遗传风险位点的功能基因组注释突显了慢性肾脏病中的炎症和上皮生物学网络。
J Am Soc Nephrol. 2015 Mar;26(3):692-714. doi: 10.1681/ASN.2014010028. Epub 2014 Sep 17.
5
Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.先天性免疫通路调节肾病基因载脂蛋白L1。
Kidney Int. 2015 Feb;87(2):332-42. doi: 10.1038/ki.2014.270. Epub 2014 Aug 6.
6
Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial.在收缩压干预试验中，载脂蛋白L1基因变异与普遍存在的肾脏疾病相关，但与普遍存在的心血管疾病无关。
Kidney Int. 2015 Jan;87(1):169-75. doi: 10.1038/ki.2014.254. Epub 2014 Jul 16.
7
Molecular mechanisms of diabetic kidney disease.糖尿病肾病的分子机制。
J Clin Invest. 2014 Jun;124(6):2333-40. doi: 10.1172/JCI72271. Epub 2014 Jun 2.
8
Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.携带 APOL1 基因突变的个体心血管疾病负担增加。
Circ Res. 2014 Feb 28;114(5):845-50. doi: 10.1161/CIRCRESAHA.114.302347. Epub 2013 Dec 30.
9
APOL1 risk variants, race, and progression of chronic kidney disease.APOL1 风险变异体、种族与慢性肾脏病的进展。
N Engl J Med. 2013 Dec 5;369(23):2183-96. doi: 10.1056/NEJMoa1310345. Epub 2013 Nov 9.
10
Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations.鉴定不同非洲人群中不同人类 APOL1 变异体的达尔文选择作用。
Am J Hum Genet. 2013 Jul 11;93(1):54-66. doi: 10.1016/j.ajhg.2013.05.014. Epub 2013 Jun 13.