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[头颈部的淋巴管畸形]

[Lymphatic malformations in the head and neck area].

作者信息

Wiegand S, Werner J A

机构信息

Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Gießen und Marburg (UKGM), Standort Marburg, Baldingerstraße, 35037, Marburg, Deutschland.

出版信息

HNO. 2016 Feb;64(2):133-41; quiz 142. doi: 10.1007/s00106-015-0114-6.

DOI:10.1007/s00106-015-0114-6
PMID:26820157
Abstract

Lymphatic malformations are congenital malformations of the lymphatic system. They are mainly located in the head and neck area, and grow proportional to the patients' body growth. Depending on the morphology, it can be distinguished between macrocystic, microcystic and mixed lymphatic malformations. Due to their infiltrative growth, microcystic lymphatic malformations are particularly difficult to treat. Therapeutic approaches include conventional surgical resection, laser therapy, sclerotherapy and systemic drug therapies.

摘要

淋巴管畸形是淋巴系统的先天性畸形。它们主要位于头颈部,并随患者身体生长而按比例生长。根据形态学,可区分出大囊型、微囊型和混合型淋巴管畸形。由于微囊型淋巴管畸形呈浸润性生长,因此治疗尤为困难。治疗方法包括传统手术切除、激光治疗、硬化治疗和全身药物治疗。

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[Lymphatic malformations in the head and neck area].[头颈部的淋巴管畸形]
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2
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Treatment guidelines of lymphatic malformations of the head and neck.头颈部淋巴管畸形治疗指南。
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引用本文的文献

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Diagnosis and surgical treatment of cervical macrocystic lymphatic malformations in infants.婴儿颈部大囊型淋巴管畸形的诊断与外科治疗
Exp Ther Med. 2017 Aug;14(2):1293-1298. doi: 10.3892/etm.2017.4703. Epub 2017 Jun 28.

本文引用的文献

1
Airway response to sirolimus therapy for the treatment of complex pediatric lymphatic malformations.西罗莫司治疗小儿复杂性淋巴管瘤的气道反应
Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2466-9. doi: 10.1016/j.ijporl.2015.10.031. Epub 2015 Oct 30.
2
Doxycycline sclerotherapy in children with head and neck lymphatic malformations.多西环素硬化疗法治疗儿童头颈部淋巴管畸形
J Pediatr Surg. 2015 Dec;50(12):2143-6. doi: 10.1016/j.jpedsurg.2015.08.051. Epub 2015 Sep 4.
3
Patients with lymphatic malformations who receive the immunostimulant OK-432 experience excellent long-term outcomes.
接受免疫刺激剂OK-432治疗的淋巴管畸形患者长期预后良好。
Acta Paediatr. 2015 Nov;104(11):1169-73. doi: 10.1111/apa.13086. Epub 2015 Jul 14.
4
Vascular Anomalies Classification: Recommendations From the International Society for the Study of Vascular Anomalies.血管异常分类:国际血管异常研究学会的建议
Pediatrics. 2015 Jul;136(1):e203-14. doi: 10.1542/peds.2014-3673. Epub 2015 Jun 8.
5
Sirolimus for the treatment of children with various complicated vascular anomalies.西罗莫司用于治疗患有各种复杂血管异常的儿童。
Eur J Pediatr. 2015 Dec;174(12):1579-84. doi: 10.1007/s00431-015-2572-y. Epub 2015 Jun 4.
6
Sildenafil for microcystic lymphatic malformations of the head and neck: A prospective study.西地那非治疗头颈部微囊型淋巴管畸形的前瞻性研究。
Int J Pediatr Otorhinolaryngol. 2015 Jul;79(7):980-2. doi: 10.1016/j.ijporl.2015.03.034. Epub 2015 Apr 9.
7
Efficacy of doxycycline and sodium tetradecyl sulfate sclerotherapy in pediatric head and neck lymphatic malformations.强力霉素和十四烷基硫酸钠硬化疗法治疗小儿头颈部淋巴管畸形的疗效
Int J Pediatr Otorhinolaryngol. 2015 Jun;79(6):883-887. doi: 10.1016/j.ijporl.2015.03.024. Epub 2015 Apr 6.
8
Aberrant lymphatic endothelial progenitors in lymphatic malformation development.淋巴管畸形发育中异常的淋巴管内皮祖细胞。
PLoS One. 2015 Feb 26;10(2):e0117352. doi: 10.1371/journal.pone.0117352. eCollection 2015.
9
Lymphatic malformations: diagnosis and management.淋巴管畸形:诊断与管理
Semin Pediatr Surg. 2014 Aug;23(4):178-85. doi: 10.1053/j.sempedsurg.2014.07.002. Epub 2014 Jul 15.
10
[Extracranial vascular anomalies (hemangiomas and vascular malformations) in children and adolescents--diagnosis, clinic, and therapy].儿童和青少年的颅外血管异常(血管瘤和血管畸形)——诊断、临床及治疗
Laryngorhinootologie. 2014 Mar;93 Suppl 1:S185-202. doi: 10.1055/s-0033-1363216. Epub 2014 Apr 7.