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严重下肢不对称的自体脂肪移植:4例报告

Autologous Fat Grafting in Severe Lower Extremity Asymmetries: Report of Four Cases.

作者信息

Monreal Juan

机构信息

Plastic Surgery, Hospital Moncloa.

出版信息

Cureus. 2015 Dec 13;7(12):e402. doi: 10.7759/cureus.402.

DOI:10.7759/cureus.402
PMID:26824005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4725679/
Abstract

BACKGROUND

Lower extremity asymmetries are challenging problems in plastic and aesthetic surgery practice. Regardless of their origin, atrophies and asymmetries can be extremely varied and difficult to solve with simple techniques.

OBJECTIVES

The author reports his experience in the treatment of four patients suffering from severe lower extremity atrophy and asymmetry of different etiologies with autologous fat grafting.

METHODS

A total of four cases are presented. Patient selection was based on the severity of atrophy and asymmetry. Two patients were treated with two sessions of simple fat grafting and two patients with one session of cell-enriched fat grafting. The end point in each session was determined by tension/blanching of soft tissues. All patients were followed up for at least 12 months after the last session. During the postoperative follow-up, variables, such as objective volume improvement, objective girth loss, return to daily activities, and patient satisfaction, were analyzed.

RESULTS

The initial analysis of postoperative results showed a good patient satisfaction rate with no relevant complications and an early return to daily activities. Estimated mean volume improvement for simple fat grafting cases was estimated as 44% after two treatments. Mean volume improvement in cell-enriched fat grafting cases was estimated as 25% after only one treatment.

CONCLUSIONS

Autologous fat grafting is a safe, effective, and reliable technique to perform aesthetic and reconstructive reshaping of a lower extremity in cases of atrophy or severe asymmetry. Depending on the preoperative soft tissue compliance, cell-assisted fat grafting will play an important role in reducing the number of sessions to perform.

摘要

背景

下肢不对称是整形和美容外科实践中具有挑战性的问题。无论其起源如何,萎缩和不对称情况可能极其多样,难以用简单技术解决。

目的

作者报告其使用自体脂肪移植治疗4例不同病因导致的严重下肢萎缩和不对称患者的经验。

方法

共呈现4例病例。根据萎缩和不对称的严重程度选择患者。2例患者接受了两期单纯脂肪移植治疗,2例患者接受了一期富细胞脂肪移植治疗。每期的终点由软组织的张力/变白情况确定。所有患者在最后一期治疗后至少随访12个月。在术后随访期间,分析了客观体积改善、客观周长减少、恢复日常活动和患者满意度等变量。

结果

术后结果的初步分析显示患者满意度良好,无相关并发症,且能早期恢复日常活动。单纯脂肪移植病例经两次治疗后估计平均体积改善率为44%。富细胞脂肪移植病例仅经一次治疗后估计平均体积改善率为25%。

结论

自体脂肪移植是一种安全、有效且可靠的技术,可用于在下肢萎缩或严重不对称的情况下进行美学和重建性重塑。根据术前软组织的顺应性,细胞辅助脂肪移植将在减少治疗次数方面发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/7f153008cd94/cureus-0007-000000000402-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/b2e36267421c/cureus-0007-000000000402-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/8993e27a67bd/cureus-0007-000000000402-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/c33de0e53a02/cureus-0007-000000000402-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/68f1a2976d7e/cureus-0007-000000000402-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/7f153008cd94/cureus-0007-000000000402-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/b2e36267421c/cureus-0007-000000000402-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/8993e27a67bd/cureus-0007-000000000402-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/c33de0e53a02/cureus-0007-000000000402-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/68f1a2976d7e/cureus-0007-000000000402-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d92/4725679/7f153008cd94/cureus-0007-000000000402-i05.jpg

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本文引用的文献

1
Do Stem Cells Have an Effect When We Fat Graft?我们进行脂肪移植时干细胞会起作用吗?
Ann Plast Surg. 2016 Jun;76 Suppl 4:S359-63. doi: 10.1097/SAP.0000000000000658.
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Calf Augmentation and Reshaping with Autologous Fat Grafting.自体脂肪移植隆乳及重塑
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Fat grafting versus adipose-derived stem cell therapy: distinguishing indications, techniques, and outcomes.脂肪移植与脂肪来源干细胞治疗:适应证、技术和结果的鉴别。
Aesthetic Plast Surg. 2012 Jun;36(3):704-13. doi: 10.1007/s00266-011-9835-4. Epub 2011 Nov 9.
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Aesthet Surg J. 2003 May;23(3):213-6. doi: 10.1067/maj.2003.44.
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Analysis of a series of autologous fat tissue transfer for lower limb atrophies.一系列自体脂肪组织移植治疗下肢萎缩的分析
Ann Plast Surg. 2008 Nov;61(5):537-43. doi: 10.1097/SAP.0b013e318164088f.
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Calf augmentation with autologous tissue injection.自体组织注射隆小腿
Plast Reconstr Surg. 2008 Jun;121(6):2127-2133. doi: 10.1097/PRS.0b013e3181708152.
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Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem/stromal cells.细胞辅助脂肪移植用于美容隆乳:脂肪来源干细胞/基质细胞的辅助应用
Aesthetic Plast Surg. 2008 Jan;32(1):48-55; discussion 56-7. doi: 10.1007/s00266-007-9019-4. Epub 2007 Sep 1.
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Cell-assisted lipotransfer: supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection.细胞辅助脂肪移植:利用人脂肪来源细胞辅助脂肪注射进行软组织填充
Tissue Eng. 2006 Dec;12(12):3375-82. doi: 10.1089/ten.2006.12.3375.
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Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells.脂肪抽吸物移植用于放射治疗组织损伤的临床治疗:由脂肪来源的成体干细胞介导的愈合过程。
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Plast Reconstr Surg. 2005 Jul;116(1):295-305; discussion 306-7. doi: 10.1097/01.prs.0000170050.86464.8e.