跨细胞途径是哺乳动物乳汁中存在纤溶酶原的最可能解释。

Transcellular route as the most probable explanation for the presence of plasminogen in mammal׳s milk.

作者信息

Silanikove Nissim

机构信息

Nissim Silanikove, Agricultural Research Organisation, Institute of Animal Science, Biology of Lactation Laboratory, PO Box 6, Bet Dagan 50250, Israel.

出版信息

J Theor Biol. 2016 Apr 21;395:221-226. doi: 10.1016/j.jtbi.2016.01.025. Epub 2016 Jan 27.

DOI:10.1016/j.jtbi.2016.01.025

PMID:26826486

Abstract

Paracellular and transcellular route of passage of several milk metabolites, albumin, lactic acid dehydrogenase and plasminogen from the systemic circulation to milk is considered. The shortcoming of prevalence views considering paracellular leakage as the most probable explanation is highlighted. A detailed discussion explaining why transcellular route is the most probable explanation for the presence of plasminogen in milk is presented.

摘要

本文考虑了几种牛奶代谢物、白蛋白、乳酸脱氢酶和纤溶酶原从体循环进入乳汁的细胞旁和跨细胞途径。文中强调了将细胞旁渗漏视为最可能解释的普遍观点的不足之处。本文详细讨论了解释为什么跨细胞途径是乳汁中存在纤溶酶原的最可能解释。