通过铜催化（邻炔基）芳基酮与胺的氨基苯并环化反应合成α-氨基萘
Synthesis of α-Aminonaphthalenes via Copper-Catalyzed Aminobenzannulation of (o-Alkynyl)arylketones with Amines.
作者信息
Zhang Mingliang, Ruan Wenqing, Zhang Hui-Jun, Li Weiwei, Wen Ting-Bin
机构信息
Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, Fujian, P. R. China.
出版信息
J Org Chem. 2016 Feb 19;81(4):1696-703. doi: 10.1021/acs.joc.5b02340. Epub 2016 Feb 1.
PMID:26828115
Abstract
A copper-catalyzed aminobenzannulation of (o-alkynyl)arylketones with amines has been developed. This method features the use of a cheap copper catalyst, the facile annulation involving various amines, and the good functional group tolerance.
摘要
已开发出一种铜催化的（邻炔基）芳基酮与胺的氨基苯并环化反应。该方法具有使用廉价铜催化剂、涉及各种胺的简便环化以及良好的官能团耐受性等特点。
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