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白色念珠菌引起的食管炎

[Esophagitis caused by Candida albicans].

作者信息

Riestra Menéndez S, Sleiman Halabi H, Suárez González A, Rodrigo Sáez L

出版信息

Rev Esp Enferm Apar Dig. 1989 Aug;76(2):188-93.

PMID:2682835
Abstract

The topic of esophagitis due to Candida (ED), the most frequent infection of the esophagus, is reviewed. In recent years we have seen increased interest in candida esophagitis, fundamentally due to its relation with AIDS, for which it constitutes a diagnostic criteria. Candida esophagitis, although it can appear in apparently healthy subjects, is usually associated with processes that impair the immune system, as well as with local lesions of the esophagus. The typical clinical presentation is as odynophagia, dysphagia and/or retrosternal pain, although asymptomatic forms are frequent, and its association with oropharyngeal candidiasis is variable. Oral endoscopy is the diagnostic technique of choice, since it permits samples to be taken for histologic and cytologic study and cultures; cytology is the most sensitive and specific technique. The differential diagnosis should be made fundamentally with other infectious esophagitis pictures, particularly herpes, and with reflux esophagitis. Treatment is based on antifungal drugs, most frequently nystatin, amphotericin B and ketoconazole.

摘要

本文综述了念珠菌性食管炎(ED)这一最常见的食管感染性疾病。近年来,我们发现对念珠菌性食管炎的关注度有所增加,这主要是因为它与艾滋病有关,是艾滋病的一项诊断标准。念珠菌性食管炎虽然可出现在看似健康的个体中,但通常与损害免疫系统的疾病以及食管局部病变有关。典型的临床表现为吞咽疼痛、吞咽困难和/或胸骨后疼痛,不过无症状形式也很常见,且其与口腔念珠菌病的关联情况不一。食管内镜检查是首选的诊断技术,因为它能获取样本进行组织学、细胞学研究及培养;细胞学检查是最敏感且特异的技术。鉴别诊断主要应与其他感染性食管炎表现,尤其是疱疹性食管炎,以及反流性食管炎相区分。治疗基于抗真菌药物,最常用的是制霉菌素、两性霉素B和酮康唑。

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