Salamanca Gómez F
Rev Invest Clin. 1989 Jul-Sep;41(3):265-86.
The most outstanding contributions of human cytogenetics in clinical investigation and in medical practice are reviewed. The perspectives of knowledge in chromosomic structure and function, in gene mapping and in the study of infertility, mutagenesis and evolution, as well as in the study of human behavior and in neurologic diseases, the prevention of congenital malformations using prenatal diagnosis techniques, and the therapeutic possibilities of chromosomic sorting are discussed. The necessity of supporting biomedical research, particularly molecular cytogenetics in underdeveloped countries, is emphasized.
本文回顾了人类细胞遗传学在临床研究和医学实践中最杰出的贡献。讨论了在染色体结构与功能、基因图谱绘制、不育症研究、诱变与进化研究、人类行为研究以及神经疾病研究等方面的知识前景，还探讨了利用产前诊断技术预防先天性畸形以及染色体分选的治疗可能性。强调了在欠发达国家支持生物医学研究，尤其是分子细胞遗传学研究的必要性。
