Rupasinghe H P Vasantha
Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia B2N 5E3, Canada.
Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia B2N 5E3, Canada.
Bioorg Chem. 2016 Apr;65:17-25. doi: 10.1016/j.bioorg.2016.01.005. Epub 2016 Jan 23.
This work compares a highly efficient and alternative method of sonication-assisted lipase catalyzed acylation of quercetin-3-O-glucoside and phloretin-2'-glucoside, using Candida antarctica lipase B (Novozyme 435(®)), with a range of fatty acids. In this study, sonication-assisted irradiation coupled with stirring has been found to be more efficient and economical than conventional reaction conditions. Sonication-assisted acylation accelerated the reactions and reduced the time required by 4-5 folds.
这项工作比较了一种高效且替代的方法，即使用南极假丝酵母脂肪酶B（诺维信435®）对槲皮素-3-O-葡萄糖苷和根皮素-2'-葡萄糖苷进行超声辅助脂肪酶催化酰化反应，并使用了一系列脂肪酸。在本研究中，已发现超声辅助辐照结合搅拌比传统反应条件更高效且经济。超声辅助酰化加速了反应，并将所需时间减少了4至5倍。
