使用聚乙二醇包覆的C18和C30树脂分离高锝[（99m）Tc]酸盐和钼酸盐。
Separation of [(99m)Tc]pertechnetate and molybdate using polyethylene glycol coated C18 and C30 resins.
作者信息
Andersson J D, Wilson J S, Romaniuk J A, McEwan A J B, Abrams D N, McQuarrie S A, Gagnon K
机构信息
University of Alberta, Medical Isotope and Cyclotron Facility, Edmonton, AB, Canada.
Edmonton PET Centre, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada.
出版信息
Appl Radiat Isot. 2016 Apr;110:193-199. doi: 10.1016/j.apradiso.2016.01.016. Epub 2016 Jan 19.
Hydrophobic adsorbents such as C18 and C30 were coated with PEG and subsequently used for the separation of Mo/Tc. The most effective resin for adsorbing PEG was the C18-U resin, which demonstrated a coating capacity of 97.6±2.8mg PEG per g of resin. The ability to adsorb pertechnetate was proportional to the amount of PEG coated on the hydrophobic resin. The [(99m)Tc]pertechnetate recovery during the separation of cyclotron produced (99m)Tc from (100)Mo was 91.8±0.3% (n=2). The resultant product met relevant USP monograph specifications.
疏水性吸附剂如C18和C30用聚乙二醇（PEG）进行包被，随后用于钼/锝的分离。吸附PEG最有效的树脂是C18-U树脂，其表现出每克树脂97.6±2.8毫克PEG的包被量。高锝酸盐的吸附能力与包被在疏水树脂上的PEG量成正比。从钼-100中分离回旋加速器产生的锝-99m期间，高锝[（99m）Tc]酸盐的回收率为91.8±0.3%（n=2）。所得产品符合美国药典相关专著规范。
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